Featured Research

from universities, journals, and other organizations

Precision Radiation Therapy Yields Rare Success For Liver Tumors

Date:
October 24, 2005
Source:
University of Rochester Medical Center
Summary:
Shaped-beam radiation therapy is a promising treatment for life-threatening metastatic liver tumors, according to researchers who report an 88 percent success rate for controlling the lesions. This is the first evidence that doctors can treat these tumors with radiation, and the results doubled the average length of survival.

Shaped-beam radiation therapy is a promising treatment for life-threatening metastatic liver tumors, according to researchers at the University of Rochester Medical Center who report an 88 percent success rate for controlling the lesions. This is the first evidence that doctors can treat these tumors with radiation, and the results doubled the average length of survival.

"Radiation therapy has not been a recommended treatment for liver metastases because of the poor results when whole-liver radiation was used," said Alan Katz, M.D., M.P.H., lead researcher and assistant professor of Radiation Oncology. "High-dose, precision radiation therapy is proving to be a promising therapy for metastatic liver disease and provides an effective treatment option for patients who previously didn't have any."

Radiation oncologists at the University's James P. Wilmot Cancer Center are leading the effort to expand shaped-beam radiation therapy -- originally designed to treat brain tumors -- to target metastatic liver tumors with pinpoint accuracy. Initial treatment results were presented this week at the American Society for Therapeutic Radiology and Oncology's annual meeting in Denver.

Many forms of cancer are treated with radiation therapy, but tumors in the liver are difficult to target using conventional techniques because the organ moves during breathing. Shaped-beam radiation therapy, also known as stereotactic body radiation therapy, has expanded treatment options by delivering a high dose of radiation precisely to the tumor, while limiting the damage to healthy tissue surrounding the tumor.

In Rochester, doctors treated 72 patients with metastatic liver lesions between April 2001 and October 2004. Most of the patients had colorectal, breast, pancreatic, lung, genitourinary, esophageal and ovarian cancers, which had spread to the liver. The patients had a median of two lesions that ranged from 0.5 centimeters to 12.2 centimeters in diameter.

Doctors followed the patients' progress for an average of a year, though some were followed as long as three years, and the average survival was 13 months.

"This is remarkable. For people who are facing this deadly disease, doubling the length of survival brings hope to our patients and that is so important," Katz said.

Katz led the research, along with Paul Okunieff, M.D., chair of Radiation Oncology, Michael Schell, Ph.D., Christine Huggins, Ph.D., and Madeleine Carey Sampson, M.D.

The Wilmot Cancer Center has been leading the research into expanding the use of stereotactic radiation therapy to treat tumors throughout the body. For the past five years, radiation oncologists have been studying its use in treating a variety of primary and metastatic tumors throughout the body and developing models for delivering radiation to organs that cannot be immobilized, such as the lungs and liver.


Story Source:

The above story is based on materials provided by University of Rochester Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University of Rochester Medical Center. "Precision Radiation Therapy Yields Rare Success For Liver Tumors." ScienceDaily. ScienceDaily, 24 October 2005. <www.sciencedaily.com/releases/2005/10/051024082032.htm>.
University of Rochester Medical Center. (2005, October 24). Precision Radiation Therapy Yields Rare Success For Liver Tumors. ScienceDaily. Retrieved July 26, 2014 from www.sciencedaily.com/releases/2005/10/051024082032.htm
University of Rochester Medical Center. "Precision Radiation Therapy Yields Rare Success For Liver Tumors." ScienceDaily. www.sciencedaily.com/releases/2005/10/051024082032.htm (accessed July 26, 2014).

Share This




More Health & Medicine News

Saturday, July 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins