Featured Research

from universities, journals, and other organizations

Top Ten Contact Dermatitis Allergens Identified In Mayo Clinic Study

Date:
March 3, 2006
Source:
Mayo Clinic
Summary:
A new Mayo Clinic study reveals the most common causes of allergic contact dermatitis, a skin inflammation resulting in swollen, reddened and itchy skin due to direct contact with an allergen.

A new Mayo Clinic study reveals the most common causes of allergic contact dermatitis, a skin inflammation resulting in swollen, reddened and itchy skin due to direct contact with an allergen. Topping the list were:

  • Nickel (nickel sulfate hexahydrate) -- metal frequently encountered in jewelry and clasps or buttons on clothing
  • Gold (gold sodium thiosulfate) -- precious metal often found in jewelry
  • Balsam of Peru (myroxylon pereirae) -- a fragrance used in perfumes and skin lotions, derived from tree resin
  • Thimerosal -- a mercury compound used in local antiseptics and in vaccines
  • Neomycin sulfate -- a topical antibiotic common in first aid creams and ointments, also found occasionally in cosmetics, deodorant, soap and pet food
  • Fragrance mix -- a group of the eight most common fragrance allergens found in foods, cosmetic products, insecticides, antiseptics, soaps, perfumes and dental products
  • Formaldehyde -- a preservative with multiple uses, e.g., in paper products, paints, medications, household cleaners, cosmetic products and fabric finishes
  • Cobalt chloride -- metal found in medical products; hair dye; antiperspirant; objects plated in metal such as snaps, buttons or tools; and in cobalt blue pigment
  • Bacitracin -- a topical antibiotic
  • Quaternium 15 -- preservative found in cosmetic products such as self-tanners, shampoo, nail polish and sunscreen or in industrial products such as polishes, paints and waxes

This study, to be presented Monday at the American Academy of Dermatology annual meeting in San Francisco, confirmed that patch testing with a standard contact dermatitis series of substances is useful for identifying common contact allergens. Patch testing is conducted by placing potential allergens covered with patches on patients' backs for two days and then observing which substances cause skin inflammation. The study confirmed previous findings by the North American Contact Dermatitis Group.

The researchers examined contact dermatitis testing results from 3,854 patients over a five-year period between Jan. 1, 2001 and Dec. 31, 2005. The patients were tested with an average of 69 allergens. Of these patients, 2,663 (69 percent) had at least one positive reaction, and 1,933 (50 percent) had two or more positive reactions.

Results of two other Mayo Clinic studies on contact dermatitis will be presented at the American Contact Dermatitis Society meeting, which immediately precedes the American Academy of Dermatology meeting. In the first study, researchers mailed a written survey to 1,458 recently tested contact dermatitis patients. The survey found that, overall, patients were satisfied with the contact dermatitis patch testing process and with subsequent improvement of their skin conditions. More than 75 percent of respondents said they were at least "somewhat satisfied" with the overall testing and treatment process, and over one-half reported they were "very satisfied." Nearly 60 percent indicated improvement in their skin conditions since the patch testing.

In the second study to be presented at the American Contact Dermatitis Society meeting, researchers included a write-in question with the aforementioned survey mailing. The survey found patients could recall only 50.6 percent of the allergens for which they tested positive an average of 13.4 months after patch testing. The researchers indicate these findings point to the ongoing need for education to remind patients of their allergens and reinforce the importance of avoiding them.

Contact dermatitis is common among all age groups and can cause minor annoyance to more severe handicaps, according to Mark Davis, M.D., Mayo Clinic dermatologist and lead study researcher. "Patients with contact dermatitis can get a very itchy rash from head to toe, or in a confined area," he says. "If it's on the hands and feet it can be disabling, and patients at times can't do their jobs."

Allergen avoidance is the chief treatment for contact dermatitis, according to Dr. Davis, though at times corticosteroid creams are used to treat rashes. He notes, however, that 3 percent of patients with contact dermatitis are allergic to the topical steroids that would alleviate their symptoms.



Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Top Ten Contact Dermatitis Allergens Identified In Mayo Clinic Study." ScienceDaily. ScienceDaily, 3 March 2006. <www.sciencedaily.com/releases/2006/03/060303204044.htm>.
Mayo Clinic. (2006, March 3). Top Ten Contact Dermatitis Allergens Identified In Mayo Clinic Study. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2006/03/060303204044.htm
Mayo Clinic. "Top Ten Contact Dermatitis Allergens Identified In Mayo Clinic Study." ScienceDaily. www.sciencedaily.com/releases/2006/03/060303204044.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins