Featured Research

from universities, journals, and other organizations

Drug Improves Memory Loss For Traumatic Brain Injury Patients

Date:
September 18, 2006
Source:
American Academy of Neurology
Summary:
Traumatic brain injury patients with moderate to severe memory loss improved their memories while taking the drug rivastigmine, according to a study published in the September 12, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology.

Traumatic brain injury patients with moderate to severe memory loss improved their memories while taking the drug rivastigmine, according to a study published in the September 12, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology.

Related Articles


Researchers, who examined 134 men and women with traumatic brain injury at 19 centers across the United States, found attention and verbal memory test scores significantly improved among severely impaired patients who took rivastigmine for 12 weeks compared to placebo-treated patients. In one test, 30-percent of patients taking rivastigmine remembered five or more additional words, compared to 10-percent in the group receiving placebo. Rivastigmine is thought to enhance the function of acetylcholine, a neurotransmitter involved in memory and learning.

"With an estimated 1.5 million people suffering from traumatic brain injury each year in the United States, rivastigmine shows promising results for these patients with moderate to severe memory loss," said the study's lead author Jonathan M. Silver, MD, with the New York School of Medicine in New York.

While rivastigmine improved memory loss for patients with moderate to severe memory impairment, the study found the drug wasn't as helpful for patients with less severe memory loss.

"The beneficial effect of rivastigmine may not become apparent unless there is significant depletion of cholinergic activity in relevant brain regions causing a more profound impairment in memory or attention," said Silver. "This is an area where more research will be required to confirm these findings and to better define who may have the best response with rivastigmine."

The study found rivastigmine was safe and well-tolerated. The most common side effects were nausea, upper respiratory tract infection, headache, dizziness and vomiting, each of which was reported in at least 10% of patients in the rivastigmine group.

Over five million people in the United States are currently living with a disability related to traumatic brain injury.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Drug Improves Memory Loss For Traumatic Brain Injury Patients." ScienceDaily. ScienceDaily, 18 September 2006. <www.sciencedaily.com/releases/2006/09/060915204436.htm>.
American Academy of Neurology. (2006, September 18). Drug Improves Memory Loss For Traumatic Brain Injury Patients. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2006/09/060915204436.htm
American Academy of Neurology. "Drug Improves Memory Loss For Traumatic Brain Injury Patients." ScienceDaily. www.sciencedaily.com/releases/2006/09/060915204436.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Former NFL Players Donate Brains to Science

Former NFL Players Donate Brains to Science

Reuters - US Online Video (Mar. 3, 2015) Super Bowl champions Sidney Rice and Steve Weatherford donate their brains, post-mortem, to scientific research into repetitive brain trauma. Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
Alzheimer's Protein Plaque Found In 20-Year-Olds

Alzheimer's Protein Plaque Found In 20-Year-Olds

Newsy (Mar. 3, 2015) Researchers found an abnormal protein associated with Alzheimer&apos;s disease in the brains of 20-year-olds. Video provided by Newsy
Powered by NewsLook.com
This Nasal Treatment Could Help Ease Migraine Pain

This Nasal Treatment Could Help Ease Migraine Pain

Newsy (Mar. 2, 2015) Researchers gave lidocaine to 112 patients, and about 88 percent of the subjects said they needed less migraine-relief medicine the next day. Video provided by Newsy
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins