Featured Research

from universities, journals, and other organizations

Drug Improves Memory Loss For Traumatic Brain Injury Patients

Date:
September 18, 2006
Source:
American Academy of Neurology
Summary:
Traumatic brain injury patients with moderate to severe memory loss improved their memories while taking the drug rivastigmine, according to a study published in the September 12, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology.

Traumatic brain injury patients with moderate to severe memory loss improved their memories while taking the drug rivastigmine, according to a study published in the September 12, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology.

Researchers, who examined 134 men and women with traumatic brain injury at 19 centers across the United States, found attention and verbal memory test scores significantly improved among severely impaired patients who took rivastigmine for 12 weeks compared to placebo-treated patients. In one test, 30-percent of patients taking rivastigmine remembered five or more additional words, compared to 10-percent in the group receiving placebo. Rivastigmine is thought to enhance the function of acetylcholine, a neurotransmitter involved in memory and learning.

"With an estimated 1.5 million people suffering from traumatic brain injury each year in the United States, rivastigmine shows promising results for these patients with moderate to severe memory loss," said the study's lead author Jonathan M. Silver, MD, with the New York School of Medicine in New York.

While rivastigmine improved memory loss for patients with moderate to severe memory impairment, the study found the drug wasn't as helpful for patients with less severe memory loss.

"The beneficial effect of rivastigmine may not become apparent unless there is significant depletion of cholinergic activity in relevant brain regions causing a more profound impairment in memory or attention," said Silver. "This is an area where more research will be required to confirm these findings and to better define who may have the best response with rivastigmine."

The study found rivastigmine was safe and well-tolerated. The most common side effects were nausea, upper respiratory tract infection, headache, dizziness and vomiting, each of which was reported in at least 10% of patients in the rivastigmine group.

Over five million people in the United States are currently living with a disability related to traumatic brain injury.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Drug Improves Memory Loss For Traumatic Brain Injury Patients." ScienceDaily. ScienceDaily, 18 September 2006. <www.sciencedaily.com/releases/2006/09/060915204436.htm>.
American Academy of Neurology. (2006, September 18). Drug Improves Memory Loss For Traumatic Brain Injury Patients. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2006/09/060915204436.htm
American Academy of Neurology. "Drug Improves Memory Loss For Traumatic Brain Injury Patients." ScienceDaily. www.sciencedaily.com/releases/2006/09/060915204436.htm (accessed September 16, 2014).

Share This



More Mind & Brain News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
'Magic Mushrooms' Could Help Smokers Quit

'Magic Mushrooms' Could Help Smokers Quit

Newsy (Sep. 11, 2014) In a small study, researchers found that the majority of long-time smokers quit after taking psilocybin pills and undergoing therapy sessions. Video provided by Newsy
Powered by NewsLook.com
'Fat Shaming' Might Actually Cause Weight Gain

'Fat Shaming' Might Actually Cause Weight Gain

Newsy (Sep. 11, 2014) A study for University College London suggests obese people who are discriminated against gain more weight than those who are not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins