Featured Research

from universities, journals, and other organizations

Appetite Changes, Depression Signal Impulse Control Disorders In Parkinson Disease

Date:
October 11, 2006
Source:
American Academy of Neurology
Summary:
Parkinson disease patients who develop impulse control disorders as a result of treatment are more likely to be depressed, irritable and have appetite changes, according to a study published in the October 10, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology. These findings could allow early identification of patients at risk for developing this distressing complication of treatment.

Parkinson disease patients who develop impulse control disorders as a result of treatment are more likely to be depressed, irritable, and have appetite changes, according to a study published in the October 10, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology. These findings could allow early identification of patients at risk for developing this distressing complication of treatment.

Related Articles


Compulsive gambling, hypersexuality, and excessive shopping have been linked to treatment with dopamine agonists in small numbers of patients. It is unknown exactly how many patients experience such an impulse control disorder, although it is believed to be less than 10 percent of those receiving these drugs.

To identify risk factors for development of impulse control disorder, the authors studied 100 Parkinson disease patients, including 66 men and 34 women, who were receiving the full range of standard anti-Parkinson medications, including levodopa, dopamine agonists, and other drugs. They administered a standard battery of psychiatric tests to identify the presence of depression, anxiety, delusions, and other psychiatric conditions, as well as impulse control disorder.

They found that nine of the 100 patients had an impulse control disorder, including four with pathological gambling, two with hypersexuality, one with excessive shopping, and two with both hypersexuality and excessive shopping. All nine were receiving a dopamine agonist, in addition to other medications.

Compared to patients without an impulse control disorder, patients with one were more than twice as likely to have depressive symptoms, were more than three times as likely to have appetite changes, and were more than six times as likely to have symptoms of irritability and disinhibition.

"These results highlight the potential usefulness of depression and appetite changes as 'sentinel symptoms' associated with an impulse control disorder," according to lead study author Laura Marsh, MD, with Johns Hopkins University School of Medicine in Baltimore, Maryland, and a member of the American Academy of Neurology. "Since only a small fraction of patients receiving dopamine agonists develop this disorder, these findings may help identify those most at risk. Strategies for treatment may include changing medications or avoiding situations that may lead to the impulsive behavior."

The study was supported by grants from the National Institutes of Health.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Appetite Changes, Depression Signal Impulse Control Disorders In Parkinson Disease." ScienceDaily. ScienceDaily, 11 October 2006. <www.sciencedaily.com/releases/2006/10/061010022953.htm>.
American Academy of Neurology. (2006, October 11). Appetite Changes, Depression Signal Impulse Control Disorders In Parkinson Disease. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2006/10/061010022953.htm
American Academy of Neurology. "Appetite Changes, Depression Signal Impulse Control Disorders In Parkinson Disease." ScienceDaily. www.sciencedaily.com/releases/2006/10/061010022953.htm (accessed October 24, 2014).

Share This



More Mind & Brain News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Academic Scandal Shocks UNC

Academic Scandal Shocks UNC

AP (Oct. 23, 2014) A scandal involving bogus classes and inflated grades at the University of North Carolina was bigger than previously reported, a new investigation found. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Working Mother Getaway: Beaches Turks & Caicos

Working Mother Getaway: Beaches Turks & Caicos

Working Mother (Oct. 22, 2014) Feast your eyes on this gorgeous family-friendly resort. Video provided by Working Mother
Powered by NewsLook.com
What Your Favorite Color Says About You

What Your Favorite Color Says About You

Buzz60 (Oct. 22, 2014) We all have one color we love to wear, and believe it or not, your color preference may reveal some of your character traits. In celebration of National Color Day, Krystin Goodwin (@kyrstingoodwin) highlights what your favorite colors may say about you. Video provided by Buzz60
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins