Featured Research

from universities, journals, and other organizations

New Evidence On Why Alcohol Consumption Is A Risk Factor For Cancer

Date:
October 31, 2006
Source:
American Chemical Society
Summary:
Why is alcohol consumption a risk factor for cancers of the oral cavity, pharynx, larynx, and esophagus? Scientists long have suspected that the culprit is acetaldehyde, a compound produced as the body breaks down the alcohol in beer, wine and hard liquor.

Why is alcohol consumption a risk factor for cancers of the oral cavity, pharynx, larynx, and esophagus? Scientists long have suspected that the culprit is acetaldehyde, a compound produced as the body breaks down the alcohol in beer, wine and hard liquor.

Now researchers in Japan have discovered direct molecular evidence supporting that link between acetaldehyde and alcohol-related cancers. In a report published in the current (October) issue of the monthly ACS journal Chemical Research in Toxicology, Tomonari Matsuda and colleagues studied DNA from the blood of 44 patients being treated for alcoholism.

They found that those patients with a variation in the aldehyde dehydrogenase gene also had increased amounts of the kind of DNA damage that can lead to cancer. The gene produces an enzyme that breaks down acetaldehyde. Individuals with the gene variant produce little aldehyde dehydrogenase and high levels of acetaldehyde build up in their blood after alcohol consumption.

Millions of people have the gene variant, which occurs mainly in individuals of East Asian heritage.

"Taken together, the observations from biochemical, epidemiological, and molecular studies, in conjunction with this study, well fit the scenario that acetaldehyde is a primary causative factor in alcohol-induced cancers," the scientists report.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "New Evidence On Why Alcohol Consumption Is A Risk Factor For Cancer." ScienceDaily. ScienceDaily, 31 October 2006. <www.sciencedaily.com/releases/2006/10/061030120516.htm>.
American Chemical Society. (2006, October 31). New Evidence On Why Alcohol Consumption Is A Risk Factor For Cancer. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2006/10/061030120516.htm
American Chemical Society. "New Evidence On Why Alcohol Consumption Is A Risk Factor For Cancer." ScienceDaily. www.sciencedaily.com/releases/2006/10/061030120516.htm (accessed October 22, 2014).

Share This



More Mind & Brain News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
Portable Breathalyzer Gets You Home Safely

Portable Breathalyzer Gets You Home Safely

Buzz60 (Oct. 21, 2014) Breeze, a portable breathalyzer, gets you home safely by instantly showing your blood alcohol content, and with one tap, lets you call an Uber, a cab or a friend from your contact list to pick you up. Sean Dowling (@SeanDowlingTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Your Birth Season Might Determine Your Temperament

Your Birth Season Might Determine Your Temperament

Newsy (Oct. 20, 2014) A new study says the season you're born in can determine your temperament — and one season has a surprising outcome. Video provided by Newsy
Powered by NewsLook.com
Movies Might Desensitize Violence For Parents, Not Just Kids

Movies Might Desensitize Violence For Parents, Not Just Kids

Newsy (Oct. 20, 2014) A study suggests that parents become desensitized to violent movies as well as children, which leads them to allow their kids to view violent films. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins