Featured Research

from universities, journals, and other organizations

Faulty Gene Linked To Prostate Cancer Risk

Date:
November 2, 2006
Source:
BMJ Specialty Journals
Summary:
Missing sections of a gene, which programs the manufacture of a chemical to alert the body to DNA damage, almost doubles the risk of prostate cancer, reveals research published ahead of print in the Journal of Medical Genetics.

Missing sections of a gene, which programmes the manufacture of a chemical to alert the body to DNA damage, almost doubles the risk of prostate cancer, reveals research published ahead of print in the Journal of Medical Genetics.

The researchers assessed almost 2,000 Polish men who had been diagnosed with prostate cancer between 1999 and 2005 to see if they carried the CHEK2 kinase gene, or CHEK2 for short.

The findings were compared with those from almost 5,500 healthy people from the general population..

The same missing sections (exons 9 and 10) were found in 24 of the healthy people (0.4%) and in 15 of the men who had been diagnosed with the disease (0.8%). They also found this deletion in four out of 249 men with familial prostate cancer.

Based on their findings, the authors calculated that this particular deletion almost doubled the risk of developing prostate cancer in general, and almost quadrupled it in men with a family history of the disease.

The authors suggest that this deletion may also be relatively common among men from other parts of eastern Europe, including the Ukraine, Belarus, Russia, the Baltic states, and countries in the Balkans.

And the findings prompt them to speculate whether the same deletion might not be carried by men elsewhere in the world.


Story Source:

The above story is based on materials provided by BMJ Specialty Journals. Note: Materials may be edited for content and length.


Cite This Page:

BMJ Specialty Journals. "Faulty Gene Linked To Prostate Cancer Risk." ScienceDaily. ScienceDaily, 2 November 2006. <www.sciencedaily.com/releases/2006/10/061031192339.htm>.
BMJ Specialty Journals. (2006, November 2). Faulty Gene Linked To Prostate Cancer Risk. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2006/10/061031192339.htm
BMJ Specialty Journals. "Faulty Gene Linked To Prostate Cancer Risk." ScienceDaily. www.sciencedaily.com/releases/2006/10/061031192339.htm (accessed August 22, 2014).

Share This




More Health & Medicine News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com
Lost Brain Cells To Blame For Sleep Problems Among Seniors

Lost Brain Cells To Blame For Sleep Problems Among Seniors

Newsy (Aug. 21, 2014) According to a new study, elderly people might have trouble sleeping because of the loss of a certain group of neurons in the brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins