Featured Research

from universities, journals, and other organizations

Underground Air Might Cause DNA Damage

Date:
December 15, 2006
Source:
Karolinska Institutet
Summary:
Our everyday environments are full of airborne particles that are harmful to varying degrees when inhaled. Particularly damaging to our cellular DNA are the particles from the underground system in Stockholm, Sweden, according to a new doctoral thesis from Karolinska Institutet.

Our everyday environments are full of airborne particles that are harmful to varying degrees when inhaled. Particularly damaging to our cellular DNA are the particles from the underground system in Stockholm, Sweden, according to a new doctoral thesis from Karolinska Institutet.

Related Articles


"Luckily, most of them do not remain in the underground for any length of time," says scientist Hanna Karlsson. "However, particle levels are often very high. My results show that there is every reason to speed up the work being done to clean the air in the underground."

Every year, some 5,300 Swedes die premature deaths from inhaling the microscopic particles of coal, asphalt, iron and other materials that pollute the city's air. These particles, which are the result of incomplete combustion, road surface attrition, etc. could be reduced if the right steps were taken; the problem is that it is not known which particle sources pose the greatest threat to human health.

To build up a picture of which particles are the most harmful, Dr Karlsson has compared how particles from a variety of sources affect cultured lung cells. The results, which are presented in her thesis Particularly harmful particles show that particles from the Stockholm underground are much more damaging to cellular DNA than the other sources tested (e.g. wood smoke and cars).

The airborne particles in the underground system largely comprise iron, and are formed by the abrasion of the train wheels against the rails. The damage is caused when these particles enter the body and form free radicals in the body's cells. Free radicals are highly reactive molecules that can prove harmful to the cell's DNA; although such damage can often be repaired by the cell, it can sometime remains untreated, and this increases the risk of cancer.

Another type of particle that stood out in the studies was that caused by the friction between car tyres and the road surface. The report shows that these particles trigger a powerful inflammatory response (i.e. a general defence reaction in the body). Levels of these particles are particularly high in the spring, when road surfaces dry out and cars are still fitted with studded winter tyres.

"It's a serious problem, as these particles exist in large concentrations in environments that people remain in for long periods," says Dr Karlsson.

Apart from particles from the underground and the roads, the study also examined those released by the combustion of wood, pellets and diesel. None of the other types of particle tested were totally harmless. Modern wood- and pellet-burning boilers gave off much fewer emissions than old ones, but the particles produced were no less harmful.


Story Source:

The above story is based on materials provided by Karolinska Institutet. Note: Materials may be edited for content and length.


Cite This Page:

Karolinska Institutet. "Underground Air Might Cause DNA Damage." ScienceDaily. ScienceDaily, 15 December 2006. <www.sciencedaily.com/releases/2006/12/061215122423.htm>.
Karolinska Institutet. (2006, December 15). Underground Air Might Cause DNA Damage. ScienceDaily. Retrieved April 21, 2015 from www.sciencedaily.com/releases/2006/12/061215122423.htm
Karolinska Institutet. "Underground Air Might Cause DNA Damage." ScienceDaily. www.sciencedaily.com/releases/2006/12/061215122423.htm (accessed April 21, 2015).

Share This


More From ScienceDaily



More Earth & Climate News

Tuesday, April 21, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deepwater And Dolphins: The Oil Spill's Impact 5 Years On

Deepwater And Dolphins: The Oil Spill's Impact 5 Years On

Newsy (Apr. 20, 2015) Five years on, the possible environmental impact of the Deepwater Horizon spill includes a sustained die-off of bottlenose dolphins, among others. Video provided by Newsy
Powered by NewsLook.com
Pee-Power Toilet to Light Up Disaster Zones

Pee-Power Toilet to Light Up Disaster Zones

Reuters - Innovations Video Online (Apr. 20, 2015) Students and staff are being asked to use a prototype urinal to &apos;donate&apos; urine to fuel microbial fuel cell (MFC) stacks that generate electricity to power lighting. The developers hope the pee-power technology will light toilet cubicles in refugee camps, where women are often at risk of assault in poorly lit sanitation areas. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Raw: Undersea Quake Shakes Taiwan

Raw: Undersea Quake Shakes Taiwan

AP (Apr. 20, 2015) A strong undersea earthquake struck between Taiwan and southern Japan on Monday, sparking a house fire that killed a person outside of Taiwan&apos;s capital. (April 20) Video provided by AP
Powered by NewsLook.com
Five Years Later, the BP Oil Spill Is Still Taking Its Toll

Five Years Later, the BP Oil Spill Is Still Taking Its Toll

AFP (Apr. 20, 2015) On April 20, 2010, an explosion and fire on the Deepwater Horizon rig in the Gulf of Mexico started the biggest oil spill in US history. BP recently reported the Gulf is recovering well, but scientists paint a different picture. Duration: 02:36 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins