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Bleeding During Endoscopy: Do Anti-inflammatories Play A Role?

Date:
March 18, 2007
Source:
McGill University Health Centre
Summary:
Does an aspirin-a-day increase the risk of bleeding during invasive diagnostic procedure? This is an important concern for many patients who take these and other antiplatelet agents in an effort to reduce heart attacks or strokes. Researchers at the MUHC have shown that antiplatelet drugs do not contribute to post-endoscopic bleeding. Their findings are published in this month's issue of Alimentary Pharmacology and Therapeutics.
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Does an aspirin-a-day increase the risk of bleeding during invasive diagnostic procedure? This is an important concern for many patients who take these and other antiplatelet agents in an effort to reduce heart attacks or strokes. Researchers at the MUHC have shown that antiplatelet drugs do not contribute to post-endoscopic bleeding. Their findings are published in this month's issue of Alimentary Pharmacology and Therapeutics.

"Clinical guidelines for use of antiplatelets during these procedures have been ambiguous," says Dr. Alan Barkun, MUHC Chief of Gastroenterology. "Some suggest withholding or stopping these medications ten days prior to the endoscopic procedure. Others will not perform the procedure if the patient was taking antiplatelet agents. In some cases this could have serious negative clinical implications. Our findings show that these precautionary measures are not necessary."

Barkun and his colleagues, including Nadeem Hussain, a clinician at the University of Western Ontario, compared the use of antiplatelets in patients who experienced bleeding with those who did not. Out of 126 endoscopy patients, they demonstrated that exposure to antiplatelets was not significantly associated with post procedure bleeding.

"Approximately 70 percent of individuals over the age of 65 are taking non steroidal anti-inflammatory medications or aspirin regularly. Our findings show that withholding these is not necessary for patients undergoing therapeutic endoscopic procedures," adds Dr. Barkun, a professor of medicine at McGill University. "This will also help ease any potential worry patients coming in for their screening colonoscopy exams may have. It is indeed important that individuals at risk for developing colorectal cancer come in for their procedures."


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The above post is reprinted from materials provided by McGill University Health Centre. Note: Materials may be edited for content and length.


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McGill University Health Centre. "Bleeding During Endoscopy: Do Anti-inflammatories Play A Role?." ScienceDaily. ScienceDaily, 18 March 2007. <www.sciencedaily.com/releases/2007/03/070315160742.htm>.
McGill University Health Centre. (2007, March 18). Bleeding During Endoscopy: Do Anti-inflammatories Play A Role?. ScienceDaily. Retrieved August 27, 2015 from www.sciencedaily.com/releases/2007/03/070315160742.htm
McGill University Health Centre. "Bleeding During Endoscopy: Do Anti-inflammatories Play A Role?." ScienceDaily. www.sciencedaily.com/releases/2007/03/070315160742.htm (accessed August 27, 2015).

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