Featured Research

from universities, journals, and other organizations

A Safe Folic Acid Boost From Flour

Date:
March 24, 2007
Source:
BioMed Central
Summary:
Public consumption of folic acid from fortified flour at current mandated US levels (100 microgram/day) and at double this amount is probably safe, at average intakes, according to an article published in the open access journal BMC Public Health. The research has implications for the UK and Republic of Ireland, which plan to follow the US by adding folic acid to flour to help prevent neural tube defects in the near future.

Public consumption of folic acid from fortified flour at current mandated US levels (100micro-gram/day) and at double this amount is probably safe, at average intakes, according to an article published in the open access journal BMC Public Health. The research has implications for the UK and Republic of Ireland, which plan to follow the US by adding folic acid to flour to help prevent neural tube defects in the near future.

Dr Mary Rose Sweeney and her colleagues from Trinity College Dublin commissioned a local bakery to bake three batches of bread, with different levels of folic acid. Single slices from the three batches contained 50micro-grams, 100micro-grams and 200micro-grams folic acid. The authors pre-saturated subjects first with daily 400micro-grams folic acid supplement, and subsequently tested them with a regime of two slices per day of the specially-prepared breads. Hourly blood tests determined whether folic acid was fully metabolised, and how long it remained in the blood.

Folic acid in bread at the 50micro-gram and 100micro-gram levels consumed twice with a 4-hour interval in between slices was fully metabolised each time. However a 400micro-gram supplement or 200micro-gram consumed once in a single slice of bread lead to metabolised folic acid in test subjects blood Long-term surveillance of the population is required to see whether folic acid accumulates, and to assess and potential safety implications.

Professor John Scott said: "this is good news in that it is possible to have optimum protection from a neural tube defect affected birth without having exposure to un-metabolised folic acid".

In fact the levels consumed currently in the US are thought to be in the range of 215-240micro-grams due to overage (the practice of adding a little extra to meet the mandate). Consumers may also get folic acid from other dietary sources, such as fortified cereals. The recommended dose for women of childbearing age in the UK is 400micro-grams per day.

Neural tube defects include spina bifida and anencephaly, which is fatal. Sufficient folic acid before and during pregnancy averts most neural tube defects. The neural tube develops in the first four weeks of pregnancy, often before many women know they are pregnant.

Article: Folic acid fortification and public health: report on threshold doses above which unmetabolised folic acid appear in serum. Mary Rose Sweeney, Joseph Mc Partlin and John Scott. BMC Public Health


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Cite This Page:

BioMed Central. "A Safe Folic Acid Boost From Flour." ScienceDaily. ScienceDaily, 24 March 2007. <www.sciencedaily.com/releases/2007/03/070322105442.htm>.
BioMed Central. (2007, March 24). A Safe Folic Acid Boost From Flour. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2007/03/070322105442.htm
BioMed Central. "A Safe Folic Acid Boost From Flour." ScienceDaily. www.sciencedaily.com/releases/2007/03/070322105442.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
American Ebola Patient Apparently Improving, Outbreak Is Not

American Ebola Patient Apparently Improving, Outbreak Is Not

Newsy (Aug. 19, 2014) Nancy Writebol, an American missionary who contracted Ebola, is apparently getting better, according to her husband. The outbreak, however, is not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins