Featured Research

from universities, journals, and other organizations

Nitric Oxide Allergic Reaction Linked To Hayfever

Date:
April 3, 2007
Source:
Society for Experimental Biology
Summary:
Hayfever is a major irritation for up to 20 percent of the population in most economically developed countries. Pollen is the cause of this allergic reaction but what causes it and why? Scientists have found evidence that nitric oxide (NO) and nitrite is released by pollen grains, and they suggest that this could be what triggers the allergic response in the nose.

Hayfever is a major irritation for up to 20% of the population in most economically developed countries. Pollen is the cause of this allergic reaction but what causes it and why?

Dr Jo Bright and Dr John Hancock of the University of the West of England have found evidence that nitric oxide (NO) and nitrite is released by pollen grains, and they suggest that this could be what triggers the allergic response in the nose. Their research was presented at the Society for Experimental Biology's Annual Main Meeting in Glasgow on 3 April.

Dr Bright says, "Our research is the first to show that pollen which is allergenic releases much greater amounts of NO and nitrite than a non-allergenic pollen."

Dr John Hancock says, "The discovery of the potential link to hayfever was made almost by accident. Whilst working on a separate project on plant reproduction we found that pollen was producing NO as a by-product. We realised that this might have implications for the allergic response many people have to pollen.

This current study has enabled us to look closely at how the plant produces NO, but we need to carry out further research so we can prove the link between the NO and the allergic reaction. These findings are very exciting and I believe they could have implications for how we treat hayfever in the future -- but there is still a lot of work to do before we can fully establish the link and we are now looking for funding so we can carry on this research."

Previous research indicates that the male parts of the plant (the pollen) may produce NO as a signal to the female parts (the stigma) during reproductive processes. NO and nitrite signalling are also important mechanisms in mammals and Dr Bright and her colleagues intend to investigate what role the pollen-derived NO and nitrite plays in human cell inflammation and irritation during hayfever.

Hiscock, S., Bright, J., McInnis, S.M., Desikan, R. & Hancock, J.T. (2007) Signaling on the Stigma: Potential New Roles for ROS and NO in Plant Cell Signaling. Plant Signaling & Behavior, 2, issue 1.

McInnis, S.M., Desikan, R., Hancock, J.T. & Hiscock, S.J. (2006) Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: potential signaling crosstalk? New Phytologist, 172, 221-228

This research is a collaboration between the University of the West of England, University of Bristol and University of Cardiff and is funded by the Wellcome Trust (grant no. 077614/Z/05/Z "The release of Nitric oxide from hay fever-causing allergens").


Story Source:

The above story is based on materials provided by Society for Experimental Biology. Note: Materials may be edited for content and length.


Cite This Page:

Society for Experimental Biology. "Nitric Oxide Allergic Reaction Linked To Hayfever." ScienceDaily. ScienceDaily, 3 April 2007. <www.sciencedaily.com/releases/2007/04/070402215230.htm>.
Society for Experimental Biology. (2007, April 3). Nitric Oxide Allergic Reaction Linked To Hayfever. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2007/04/070402215230.htm
Society for Experimental Biology. "Nitric Oxide Allergic Reaction Linked To Hayfever." ScienceDaily. www.sciencedaily.com/releases/2007/04/070402215230.htm (accessed October 22, 2014).

Share This



More Health & Medicine News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins