Featured Research

from universities, journals, and other organizations

Low-glycemic Load Diet May Be More Effective For Dieters With Certain Insulin Response Patterns

Date:
May 17, 2007
Source:
JAMA and Archives Journals
Summary:
Overweight individuals who secrete insulin at a higher level may experience greater weight loss by selecting a low-glycemic load diet, compared to a low-fat diet, according to a new study. Researchers also found a low-glycemic load diet to have beneficial effects on HDL cholesterol and triglyceride concentrations.

Overweight individuals who secrete insulin at a higher level may experience greater weight loss by selecting a low-glycemic load diet, compared to a low-fat diet, according to a study in the May 16 issue of JAMA. The researchers also found a low-glycemic load diet to have beneficial effects on HDL cholesterol and triglyceride concentrations.

"With prevalence approaching one-third of the population, obesity is among the most important medical problems in the United States and identification of effective dietary treatment has become a major public health priority. Three popular diets--low fat, low carbohydrate, and low glycemic load--have recently received much attention.

However, clinical trials have produced inconsistent findings, with some suggesting that one diet is superior for weight loss and others indicating no difference between diets," the authors write. They add that one explanation for the inconsistent findings could relate to the inherent physiological differences among study participants. "One physiological mechanism that might relate weight loss to dietary composition is individual differences in insulin secretion."

Cara B. Ebbeling, Ph.D., of Children's Hospital Boston, and colleagues conducted a study to determine whether insulin secretion affects weight loss and body fat loss among obese individuals with different diets. This randomized controlled trial, conducted from September 2004 to December 2006, included 73 obese young adults (age 18-35 years) and consisted of a 6-month intensive intervention period and a 12-month follow-up period. Serum insulin concentration at 30 minutes after a 75-g dose of oral glucose was determined at baseline as a measure of insulin secretion. Outcomes were assessed at 6, 12, and 18 months. Participants consumed either a low--glycemic load (40 percent carbohydrate and 35 percent fat) or low-fat (55 percent carbohydrate and 20 percent fat) diet.

The researchers found that change in body weight and body fat percentage did not differ between the diet groups overall. However, for those with insulin concentration at 30 minutes above the median (midpoint), the low--glycemic load diet produced a greater decrease in weight (12.8 lbs. vs. 2.6 lbs.) and body fat percentage (--2.6 percent vs. --0.9 percent) than the low-fat diet at 18 months. There were no significant differences in these end points between diet groups for those with insulin concentration at 30 minutes below the median level. Among all the participants in the study, high-density lipoprotein cholesterol (the "good" cholesterol) and triglyceride concentrations improved more on the low--glycemic load diet, whereas low-density lipoprotein cholesterol (the "bad" cholesterol) concentration improved more on the low-fat diet.

"The main finding of our study is that a simple measure of insulin secretion predicted weight and body fat loss on low--glycemic load and low-fat diets," the authors write. "For obese individuals with high insulin concentration at 30 minutes during an oral glucose tolerance test, a low--glycemic load diet may promote more weight and body fat loss than a low-fat diet. Regardless of insulin secretion, a low--glycemic load diet has beneficial effects on concentrations of HDL cholesterol and triglycerides but not on LDL cholesterol. Additional research is needed to examine these effects in other populations and to explore the mechanistic basis for the observed diet-phenotype interaction."

JAMA. 2007;297:2092-2102.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Low-glycemic Load Diet May Be More Effective For Dieters With Certain Insulin Response Patterns." ScienceDaily. ScienceDaily, 17 May 2007. <www.sciencedaily.com/releases/2007/05/070515165106.htm>.
JAMA and Archives Journals. (2007, May 17). Low-glycemic Load Diet May Be More Effective For Dieters With Certain Insulin Response Patterns. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2007/05/070515165106.htm
JAMA and Archives Journals. "Low-glycemic Load Diet May Be More Effective For Dieters With Certain Insulin Response Patterns." ScienceDaily. www.sciencedaily.com/releases/2007/05/070515165106.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins