Featured Research

from universities, journals, and other organizations

Treatment Of Thyroid Disease Reduces Tiredness And The Risk Factors For Heart Disease, According To Study

Date:
May 29, 2007
Source:
University of Newcastle upon Tyne
Summary:
Putting on weight and feeling lethargic? New research shows it is worth having your thyroid levels checked – as these can be symptoms of thyroid disease which is easily identified and treated. A new study shows treatment for a shortage of the hormone thyroxine lowers cholesterol, reverses weight gain and reduces the risk factors for heart disease.

New research from Newcastle University shows treatment for a shortage of the hormone thyroxine lowers cholesterol, reverses weight gain and reduces the risk factors for heart disease.

Related Articles


Putting on weight and feeling lethargic? New research shows it is worth having your thyroid levels checked – as these can be symptoms of thyroid disease which is easily identified and treated.

Known medically as sub clinical hypothyroidism, it is characterised by a shortage of the hormone thyroxine and often precedes an underactive thyroid.

It affects up to 16% of women and 6% of men, becoming more prevalent with age.

The research has shown that treatment of subclinical hypothyroidism with thyroid hormone reduces tiredness, cholesterol and reduces the risk factors for heart disease by improving the markers of atherosclerosis or hardening of the arteries.

In the study, patients undergoing 12 weeks of thyroxine treatment saw a reduction in their amount of LDL cholesterol, reversed weight gain - losing on average half a kilo, felt less tired and had reduced their risk factors for heart disease.

Until recently many doctors considered this condition not worthy of treatment. Now a new study led by Dr Jolanta Weaver of Newcastle University and Gateshead NHS Foundation Trust published in The Journal of Clinical Endocrinology and Metabolism shows that treatment leads to significant improvements for patients.

In the largest trial to date, 100 participants with persistent subclinical hypothyroidism were given thyroxine and compared with those taking a placebo or dummy medication.

Dr Salman Razvi and Dr Jolanta Weaver of Newcastle University’s School of Clinical Medical Sciences carried out a pivotal crossover study. They assessed common heart disease risk factors such as the level of LDL, or “bad”, cholesterol, body weight and endothelial function, which is a very early marker of hardening of the arteries. They also asked participants to rate their quality of life.

This treatment did not cause any side-effects.

Dr Weaver says, “The results of our study show that treatment of people with this mild form of underactive thyroid condition leads to significant improvements in risk factors for ischemic heart disease and symptoms of tiredness.”

Patients with subclinical hypothyroidism are being encouraged to discuss their treatment with their doctors.

Case Study

Frances King, 56, from Dunston, Gateshead.

“I took part in the study because I was first diagnosed with a borderline underactive thyroid 27 years ago but never had any treatment. I‘d never been ill but always had a lack of energy and generally felt tired and lethargic. As soon as I was put on the medication I noticed a difference. Since the trial I’ve been back to my GP and have been prescribed thyroxine. I now have more energy and feel brighter.

I’ve battled with my weight for years but since getting the medication I’ve lost a couple of stones because I’m more motivated to do things. I’ve got a real zest for life - I run up the stairs, I’ve got the energy to walk the dogs and I’m out gardening which I hadn’t been doing.”


Story Source:

The above story is based on materials provided by University of Newcastle upon Tyne. Note: Materials may be edited for content and length.


Cite This Page:

University of Newcastle upon Tyne. "Treatment Of Thyroid Disease Reduces Tiredness And The Risk Factors For Heart Disease, According To Study." ScienceDaily. ScienceDaily, 29 May 2007. <www.sciencedaily.com/releases/2007/05/070529132906.htm>.
University of Newcastle upon Tyne. (2007, May 29). Treatment Of Thyroid Disease Reduces Tiredness And The Risk Factors For Heart Disease, According To Study. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2007/05/070529132906.htm
University of Newcastle upon Tyne. "Treatment Of Thyroid Disease Reduces Tiredness And The Risk Factors For Heart Disease, According To Study." ScienceDaily. www.sciencedaily.com/releases/2007/05/070529132906.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins