Featured Research

from universities, journals, and other organizations

A Novel Approach To Cancer Therapy

Date:
June 20, 2007
Source:
University Of Surrey
Summary:
Cancer sometimes involves processes that should only occur in the embryo being mistakenly reactivated in adult cells. Researchers have exploited this to develop a novel therapeutic strategy. This has led to the development of a new drug, HXR9 that blocks the activity of a group of genes known as the HOX family.

Cancer sometimes involves processes that should only occur in the embryo being mistakenly reactivated in adult cells. Researchers at the Postgraduate Medical School at the University of Surrey have exploited this to develop a novel therapeutic strategy. This has led to the development of a new drug, HXR9 that blocks the activity of a group of genes known as the HOX family.

The project leader, Dr Richard Morgan, explains ‘HOX genes are important in determining the identity of cells and tissues in the early embryo, but they are also expressed by cancer cells. HXR9 blocks HOX activity thereby killing cancer cells in a highly specific manner’. HXR9 shows particular promise in treating malignant melanoma together with lung, prostate and kidney cancer.

Work on HXR9 was started by Dr Morgan whilst he was a senior lecturer at St. George’s, University of London, and the University of Surrey has recently agreed a licensing deal to allow Dr Morgan to continue with the work at the PGMS.

Further work by the PGMS group has shown that embryonic genes expressed in cancer cells could also be important diagnostic markers. A number of embryonic proteins are secreted by prostate tumours and can be detected in blood serum, thereby providing a potential method for detecting prostate cancer and ultimately even assessing the extent of the disease without an invasive procedure. These findings have now been patented by the University of Surrey. The results appear in 'Cancer Research’ Journal.


Story Source:

The above story is based on materials provided by University Of Surrey. Note: Materials may be edited for content and length.


Cite This Page:

University Of Surrey. "A Novel Approach To Cancer Therapy." ScienceDaily. ScienceDaily, 20 June 2007. <www.sciencedaily.com/releases/2007/06/070619164739.htm>.
University Of Surrey. (2007, June 20). A Novel Approach To Cancer Therapy. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2007/06/070619164739.htm
University Of Surrey. "A Novel Approach To Cancer Therapy." ScienceDaily. www.sciencedaily.com/releases/2007/06/070619164739.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins