Featured Research

from universities, journals, and other organizations

A Novel Approach To Cancer Therapy

Date:
June 20, 2007
Source:
University Of Surrey
Summary:
Cancer sometimes involves processes that should only occur in the embryo being mistakenly reactivated in adult cells. Researchers have exploited this to develop a novel therapeutic strategy. This has led to the development of a new drug, HXR9 that blocks the activity of a group of genes known as the HOX family.

Cancer sometimes involves processes that should only occur in the embryo being mistakenly reactivated in adult cells. Researchers at the Postgraduate Medical School at the University of Surrey have exploited this to develop a novel therapeutic strategy. This has led to the development of a new drug, HXR9 that blocks the activity of a group of genes known as the HOX family.

Related Articles


The project leader, Dr Richard Morgan, explains ‘HOX genes are important in determining the identity of cells and tissues in the early embryo, but they are also expressed by cancer cells. HXR9 blocks HOX activity thereby killing cancer cells in a highly specific manner’. HXR9 shows particular promise in treating malignant melanoma together with lung, prostate and kidney cancer.

Work on HXR9 was started by Dr Morgan whilst he was a senior lecturer at St. George’s, University of London, and the University of Surrey has recently agreed a licensing deal to allow Dr Morgan to continue with the work at the PGMS.

Further work by the PGMS group has shown that embryonic genes expressed in cancer cells could also be important diagnostic markers. A number of embryonic proteins are secreted by prostate tumours and can be detected in blood serum, thereby providing a potential method for detecting prostate cancer and ultimately even assessing the extent of the disease without an invasive procedure. These findings have now been patented by the University of Surrey. The results appear in 'Cancer Research’ Journal.


Story Source:

The above story is based on materials provided by University Of Surrey. Note: Materials may be edited for content and length.


Cite This Page:

University Of Surrey. "A Novel Approach To Cancer Therapy." ScienceDaily. ScienceDaily, 20 June 2007. <www.sciencedaily.com/releases/2007/06/070619164739.htm>.
University Of Surrey. (2007, June 20). A Novel Approach To Cancer Therapy. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/2007/06/070619164739.htm
University Of Surrey. "A Novel Approach To Cancer Therapy." ScienceDaily. www.sciencedaily.com/releases/2007/06/070619164739.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins