Featured Research

from universities, journals, and other organizations

Nanobubbles Deliver Targeted Cancer Drugs Using Ultrasound

Date:
July 13, 2007
Source:
Journal of the National Cancer Institute
Summary:
A new targeted drug delivery method uses ultrasound to image tumors, while also releasing the drug from "nanobubbles" into the tumor, according to a study published online July 10 in the Journal of the National Cancer Institute.

A new targeted drug delivery method uses ultrasound to image tumors, while also releasing the drug from "nanobubbles" into the tumor, according to a study published online July 10 in the Journal of the National Cancer Institute.

Cancer drugs can be targeted to tumors by delivering them in packets of nanoparticles, then releasing them with ultrasound. But this approach can be difficult because it requires a way to image the tumor prior to treatment.

Natalya Rapoport, Ph.D., D.Sc., of the University of Utah in Salt Lake City and colleagues describe a new method of drug delivery that may address this problem. Nanobubbles filled with the chemotherapy drug doxorubicin were injected into mice. The bubbles accumulated in the tumors, where they combined to form larger "microbubbles." When exposed to ultrasound, the bubbles generated echoes, which made it possible to image the tumor. The sound energy from the ultrasound popped the bubbles, releasing the drug. In mice treated with this method, the nanobubbles were more effective at blocking tumor growth than other nanoparticle delivery methods.

"Microbubble formulations have been developed for combining ultrasonic tumor imaging and ultrasound-enhanced chemotherapeutic treatment," the authors write.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Nanobubbles Deliver Targeted Cancer Drugs Using Ultrasound." ScienceDaily. ScienceDaily, 13 July 2007. <www.sciencedaily.com/releases/2007/07/070711143204.htm>.
Journal of the National Cancer Institute. (2007, July 13). Nanobubbles Deliver Targeted Cancer Drugs Using Ultrasound. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2007/07/070711143204.htm
Journal of the National Cancer Institute. "Nanobubbles Deliver Targeted Cancer Drugs Using Ultrasound." ScienceDaily. www.sciencedaily.com/releases/2007/07/070711143204.htm (accessed October 22, 2014).

Share This



More Health & Medicine News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins