Featured Research

from universities, journals, and other organizations

Defense Mechanism Found In Infected Ticks May Protect Against Harmful Parasite

Date:
July 17, 2007
Source:
American Society for Microbiology
Summary:
A defense molecule isolated in ticks infected with the Babesia sp. parasite may protect animals and humans against infection.

Tick on human skin after sucking blood.
Credit: iStockphoto/Gόnther Blumenstock

A defense molecule isolated in ticks infected with the Babesia sp. parasite may protect animals and humans against infection. Researchers from the U.S. and abroad report their findings in the July 2007 issue of the journal Infection and Immunity.

Related Articles


Babesiosis is a well-recognized disease worldwide and recently gained increased attention as an emerging zoonosis. Transmitted to animals and humans by ticks infected with the Bebesia sp. parasite, symptoms may include fever, fatigue and hemolytic anemia. Antimcrobial peptides are defensive molecules found in the innate immune system of animals. Less toxic and more effective against multi-drug resistant bacteria, they are showing promise as a better choice for treatment of some bacterial and fungal infectious diseases.

In the study researchers identified a novel parasiticidal peptide named longicin from the tick species Haemaphysalis longicornis and tested its ability to inhibit infection. It showed a remarkable ability to inhibit the blood stage of equine Babesia equi by killing the parasites and resulted in reduction of parasitemia in animals with the zoonotic and murine Babesia microti. RNA analysis also demonstrated that longicin is capable of killing the canine strain, Babesia gibsoni.

“Here we report a defensin peptide, longicin, from the tick H. longicornis that exerts a babesiacidal effect,” say the researchers. “Theoretically, longicin may serve as a model for the development of chemotherapeutic compounds against tick-borne disease organisms.”

Reference: N. Tsuji, B. Battsetseg, D. Boldbaatar, T. Miyoshi, X. Xuan, J.H. Oliver, Jr., K. Fujisaki. 2007. Babesial vector tick defensin against Babesia sp. Parasites. Infection and Immunity, 75. 7: 3633-3640


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Microbiology. "Defense Mechanism Found In Infected Ticks May Protect Against Harmful Parasite." ScienceDaily. ScienceDaily, 17 July 2007. <www.sciencedaily.com/releases/2007/07/070716191846.htm>.
American Society for Microbiology. (2007, July 17). Defense Mechanism Found In Infected Ticks May Protect Against Harmful Parasite. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2007/07/070716191846.htm
American Society for Microbiology. "Defense Mechanism Found In Infected Ticks May Protect Against Harmful Parasite." ScienceDaily. www.sciencedaily.com/releases/2007/07/070716191846.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) — Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) — Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) — According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) — A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins