Featured Research

from universities, journals, and other organizations

New Drug Delivery System Minimizes Side Effects

Date:
August 8, 2007
Source:
Queen's University, Belfast
Summary:
A new drug dosing system controlled by light has just been developed. The system could allow the long-sought ability to deliver drugs where, when, and in the exact doses, required. This would maximize their effect and reduce side effects and damage to healthy parts of the body.

In the future, novel medicines that are activated by light could reduce side-effects associated with drug delivery, researchers say. Experimental light-activated solution (left) undergoes transformation (right) after exposure to ultraviolet light.
Credit: Courtesy of Colin McCoy, Queen's University Belfast

A new drug dosing system controlled by light has been developed by scientists at Queen’s University Belfast. The system could allow the long-sought ability to deliver drugs where, when, and in the exact doses, required. This would maximize their effect and reduce side effects and damage to healthy parts of the body.

Dr Colin P. McCoy and colleagues from the School of Pharmacy at Queen’s describe their new molecular-scale dosing devices as “a new paradigm for precise control of drug dosing using light.”

The devices consist of medications combined with certain chemical compounds that respond to light in ways that release precisely controlled amounts of the drug. Drug release begins when light falls on the compounds, and lasts only as long as the light continues to shine.

Their study, which is reported in the Journal of the American Chemical Society, showed successful laboratory tests of the system in the controlled release of three common medications used to treat pain and inflammation — aspirin, ibuprofen and ketoprofen.

Explaining some of the potential uses for the new method, Dr McCoy said: “One potential use we cited in the study would be in the treatment of urinary catheter infections, where the drug is held latently in the catheter, and is released when needed using light from a fibre optic. The system could likewise be used for other conditions using an implant under the skin for precisely controlled drug dosing.”

Article: "Light-Triggered Molecule-Scale Drug Dosing Devices"


Story Source:

The above story is based on materials provided by Queen's University, Belfast. Note: Materials may be edited for content and length.


Cite This Page:

Queen's University, Belfast. "New Drug Delivery System Minimizes Side Effects." ScienceDaily. ScienceDaily, 8 August 2007. <www.sciencedaily.com/releases/2007/08/070805130108.htm>.
Queen's University, Belfast. (2007, August 8). New Drug Delivery System Minimizes Side Effects. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2007/08/070805130108.htm
Queen's University, Belfast. "New Drug Delivery System Minimizes Side Effects." ScienceDaily. www.sciencedaily.com/releases/2007/08/070805130108.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins