Featured Research

from universities, journals, and other organizations

Toward An Urgently Needed Antidote For Cyanide Poisoning Disasters

Date:
December 29, 2007
Source:
American Chemical Society
Summary:
Citing an "alarming" lack of preparedness for terrorist attacks or other incidents involving release of cyanide, researchers in Minnesota are announcing development of potential new antidotes for the deadly poison that can be taken by mouth rather than injection.

Citing an “alarming” lack of preparedness for terrorist attacks or other incidents involving release of cyanide, researchers in Minnesota are announcing development of potential new antidotes for the deadly poison that can be taken by mouth rather than injection.

The study is scheduled for the Dec. 27 issue of ACS’ Journal of Medicinal Chemistry, a bi-weekly publication.

In the study, Herbert Nagasawa and colleagues explain that existing antidotes for cyanide poisoning require a series of intravenous drug injections, making them cumbersome and difficult to administer in incidents in which hundreds or thousands of people are exposed. The nation thus faces an “urgent need” for a fast-acting, easy-to-use treatment that can be administered on a large scale, the researchers say. The new compounds, chemically modified versions of 3-mercaptopyruvate, change cyanide into a nontoxic substance. When given orally to laboratory mice prior to cyanide exposure, the compounds prevented poisoning, they add.

An oral drug that prevents cyanide poisoning is “highly desirable for firefighters and other rescue workers responding to industrial and residential fires where the presence of cyanide in the smoke is life-threatening,” the study states. “The new compounds can be produced in quantity for wide distribution to public health agencies for stockpiling to protect the populace in the event of a major cyanide disaster resulting from an industrial accident or terrorist activity,” the study adds.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Toward An Urgently Needed Antidote For Cyanide Poisoning Disasters." ScienceDaily. ScienceDaily, 29 December 2007. <www.sciencedaily.com/releases/2007/12/071224125429.htm>.
American Chemical Society. (2007, December 29). Toward An Urgently Needed Antidote For Cyanide Poisoning Disasters. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2007/12/071224125429.htm
American Chemical Society. "Toward An Urgently Needed Antidote For Cyanide Poisoning Disasters." ScienceDaily. www.sciencedaily.com/releases/2007/12/071224125429.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Obama: Ebola Outbreak Threat to Global Security

Obama: Ebola Outbreak Threat to Global Security

AP (Sep. 16, 2014) President Obama is ordering U.S. military personnel to West Africa to deal with the Ebola outbreak, which is he calls a potential threat to global security. (Sept. 16) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins