Featured Research

from universities, journals, and other organizations

Toward Solving The Mystery Of Idiosyncratic Drug Reactions

Date:
January 8, 2008
Source:
American Chemical Society
Summary:
A mysterious and unpredictable group of side effects from modern medications called idiosyncratic drug reactions likely will persist as a major health care problem unless there is a dramatic increase in research funding, according to a 20-year review of research in the field.

A mysterious and unpredictable group of side effects from modern medications called idiosyncratic drug reactions (IDRs) likely will persist as a major health care problem unless there is a dramatic increase in research funding, according to a 20-year review of research in the field.

Related Articles


The review, by Jack Uetrecht, defines IDRs as reactions that happen unexpectedly and with no obvious connection to the known effects of a medication's ingredients or dosage. Although relatively rare, IDRs make an important contribution to the annual burden of death, illness, and increased health care costs from serious adverse drug reactions. In addition, serious IDRs that appear after a new drug has gone into wide use can force drug companies to withdraw products after R&D investments totaling hundreds of millions of dollars.

Two decades of research have produced significant progress, the report acknowledges. However, medical science still has only a "superficial" understanding of how and why IDRs occur and a growing recognition that the mechanisms behind IDRs may be as complicated as those involved in cancer or diabetes. The review describes a need for increased research funding, with more scientists focusing on IDRs, in order to achieve faster progress.

The article "Idiosyncratic Drug Reactions: Past, Present, and Future" is scheduled for the January issue of ACS' Chemical Research in Toxicology.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Toward Solving The Mystery Of Idiosyncratic Drug Reactions." ScienceDaily. ScienceDaily, 8 January 2008. <www.sciencedaily.com/releases/2008/01/080107104539.htm>.
American Chemical Society. (2008, January 8). Toward Solving The Mystery Of Idiosyncratic Drug Reactions. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2008/01/080107104539.htm
American Chemical Society. "Toward Solving The Mystery Of Idiosyncratic Drug Reactions." ScienceDaily. www.sciencedaily.com/releases/2008/01/080107104539.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins