Featured Research

from universities, journals, and other organizations

Low Testosterone Levels Associated With Risk Of Fracture In Men Over 60

Date:
January 17, 2008
Source:
JAMA and Archives Journals
Summary:
Men over age 60 who have low blood testosterone levels may be at a higher risk for fractures, according to a new article. One-third of all osteoporotic fractures caused by porous bones occur in men.

Men over age 60 who have low blood testosterone levels may be at a higher risk for fractures, according to a new article.

Related Articles


One-third of all osteoporotic fractures caused by porous bones occur in men, according to background information in the article. Men with a previous osteoporotic fracture have three to four times the risk of having another fracture than a woman of the same age with a fracture. "Preventing the first such fracture may have major public health implications," the authors note. "Thus, understanding the determinants of fracture risk in men may reduce the burden of disease through facilitating better prevention strategies."

Christian Meier, M.D., of the University of Sydney, Concord, New South Wales, Australia, and colleagues observed 609 men (average age 72.6) between January 1989 and December 2005. The men's bone mineral density and lifestyle factors were recorded at the beginning of the study. Serum testosterone and estradiol (an estrogen) levels were measured and the occurrence of a low-trauma fracture (associated with a fall from standing height or less) was determined during follow-up.

Low-trauma fractures occurred in 113 men during follow-up with the risk of fracture significantly higher in those with low testosterone levels. "Twenty-five men experienced multiple incident fractures," the authors note. "A total of 149 incident fractures were reported, including 55 vertebral, 27 hip, 28 rib, six wrist and 16 upper and 17 lower extremity fractures."

"After adjustment for sex hormone binding globulin (a blood protein), serum testosterone and serum estradiol levels were associated with overall fracture risk," according to the authors. "After further adjustment for major risk factors of fractures (age, weight or bone mineral density, fracture history, smoking status, calcium intake and sex hormone binding globulin), lower testosterone was still associated with increased risk of fracture, particularly with hip and non-vertebral fractures."

Although low levels of estradiol and testosterone were associated with a higher risk of fracture in men over 60, only the effect of testosterone was independent of other risk factors, the authors conclude. "While testosterone may affect fracture risk via skeletal and non-skeletal mechanisms, the present findings suggest that measurement of serum testosterone provides additional clinical information for the assessment of fracture risk in elderly men."

Journal reference: Arch Intern Med. 2008;168[1]:47-54. This study was supported by the National Health and Medical Research Council of Australia; and the ARUP Institute for Clinical and Experimental Pathology. Dr. Meier is the recipient of a medical research fellowship from the Swiss National Science Foundation and a research fellowship from the Margarete und Walter Lichtenstein Stiftung der Universitδt Basel.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Low Testosterone Levels Associated With Risk Of Fracture In Men Over 60." ScienceDaily. ScienceDaily, 17 January 2008. <www.sciencedaily.com/releases/2008/01/080114162523.htm>.
JAMA and Archives Journals. (2008, January 17). Low Testosterone Levels Associated With Risk Of Fracture In Men Over 60. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2008/01/080114162523.htm
JAMA and Archives Journals. "Low Testosterone Levels Associated With Risk Of Fracture In Men Over 60." ScienceDaily. www.sciencedaily.com/releases/2008/01/080114162523.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins