Featured Research

from universities, journals, and other organizations

Neurological Basis Of Depression Following Sports Concussion Found

Date:
January 21, 2008
Source:
Montreal Neurological Institute and Hospital
Summary:
Researchers have identified the neurological basis of depression in male athletes with persisting post-concussion symptoms. The study has important clinical implications for the treatment of individuals who have suffered a cerebral concussion.

Researchers at the Montreal Neurological Institute of McGill University have identified the neurological basis of depression in male athletes with persisting post-concussion symptoms. The study, published in this week’s issue of Archives of General Psychiatry, has important clinical implications for the treatment of individuals who have suffered a cerebral concussion.

Related Articles


Depression is one of a number of persisting symptoms experienced by athletes following sports concussion. The prevalence of depression in the general population is around 5%, whilst the prevalence of depression in head trauma patients can reach an astounding 40 %. “Until now, very little was known about the neurological basis of the depression frequently reported by athletes following concussion,’ says Dr. Alain Ptito, neuropsychologist and researcher at the MNI, and lead investigator for the study.

Traditional testing methods for concussion yielded normal results with no obvious cognitive or neurological deficits. Persistent complaints have been perceived as subjective and ill-defined without neurological basis. Injury to the brain following concussion takes place at a microscopic level and is therefore difficult to measure in a patient. Using enhanced brain imaging technology, researchers are now able to gain new insights into the damage caused by concussion.

“Using functional MRI (fMRI), a computerized imaging technique that measures blood oxygen levels, we were able to detect areas of the brain with abnormal neural activity,” explained Dr. Ptito. Dr. Ptito and colleagues tested fifty-six male athletes, 40 with concussion and 16 healthy controls. Using a depression index, 16 of the concussed subjects had no symptoms of depression, 16 expressed mild depression and 8 had moderate symptoms of depressions.

Concussed athletes with depression showed reduced brain activity in regions known to be implicated in depression, specifically, the dorsolateral prefrontal cortex and striatum and attenuated deactivation in medial frontal and temporal regions. We discovered that concussed subjects with depression presented with the same pattern of brain activation as that seen for patients with major depression.”

Other studies have shown a link between a history of brain injury and probability of developing major depression later in life. Therefore understanding the pathology of depression in concussed subjects has important implications for early intervention and successful outcomes.

This study was funded by the Canadian Institutes of Health Research (CIHR) and the Fonds de la Recherche en Santé du Québec. About the MNI The Montreal Neurological Institute is a McGill University research and teaching institute, dedicated to the study of the nervous system and neurological diseases.


Story Source:

The above story is based on materials provided by Montreal Neurological Institute and Hospital. Note: Materials may be edited for content and length.


Cite This Page:

Montreal Neurological Institute and Hospital. "Neurological Basis Of Depression Following Sports Concussion Found." ScienceDaily. ScienceDaily, 21 January 2008. <www.sciencedaily.com/releases/2008/01/080118115428.htm>.
Montreal Neurological Institute and Hospital. (2008, January 21). Neurological Basis Of Depression Following Sports Concussion Found. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2008/01/080118115428.htm
Montreal Neurological Institute and Hospital. "Neurological Basis Of Depression Following Sports Concussion Found." ScienceDaily. www.sciencedaily.com/releases/2008/01/080118115428.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Tryptophan Isn't Making You Sleepy On Thanksgiving

Tryptophan Isn't Making You Sleepy On Thanksgiving

Newsy (Nov. 27, 2014) — Tryptophan, a chemical found naturally in turkey meat, gets blamed for sleepiness after Thanksgiving meals. But science points to other culprits. Video provided by Newsy
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) — Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) — Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins