Featured Research

from universities, journals, and other organizations

Urine Protein May Be Present Before Hypertension Diagnosis In At-risk Adolescents

Date:
February 29, 2008
Source:
Medical College of Georgia
Summary:
A protein that is an early indicator of kidney dysfunction in adults may predict hypertension in black adolescents, researchers have found. Researchers found that the black teens had a 10 percent higher rate of albumin in their urine than their white counterparts, despite the fact that both groups had normal blood pressure.

A protein that is an early indicator of kidney dysfunction in adults may predict hypertension in black adolescents, Medical College of Georgia researchers have found.

Related Articles


“Microalbuminuria, excessive amounts of albumin in the urine, is a common problem among diabetics,” says Dr. Gregory Harshfield, director of the Medical College of Georgia’s Georgia Prevention Institute. “For that reason, the few studies that have looked at adolescent patients have been focused on sick populations and even fewer have examined the phenomenon in healthy adolescents. What we were looking to find was the prevalence of the problem in a healthy population of children and adolescents and the impact of race, sex, sodium-handling and blood pressure on microalbuminuria.”

Dr. Harshfield and his co-investigators, Dr. Coral Hanevold, a former MCG pediatric nephrologist now at the University of Washington in Seattle, and Dr. Jennifer Pollock, an MCG pharmacologist, studied 317 healthy teens age 15-18.

The subjects were placed on a three-day sodium-controlled diet prior to testing on day four. Testing consisted of a two-hour baseline period, a one-hour stress period and a two-hour post-stress period. Urine samples were obtained at the end of each hour. Levels of microalbumin were determined following the first-hour baseline period.

Researchers found that the black teens had a 10 percent higher rate of albumin in their urine than their white counterparts, despite the fact that both groups had normal blood pressure. Those results suggest that kidney damage in these high-risk youths is apparent even before the development of high blood pressure. The black girls had a 22 percent higher albumin excretion rate than white girls.

The higher levels correspond to a tendency to retain sodium after stress, Dr. Harshfield says, noting that sodium retention is normal during stress but should normalize after the stressor has passed.

“What we’ve shown is that children and adolescents, particularly black children, can display reduced kidney function prior to the onset of hypertension. Therefore, it would be prudent to measure levels of microalbuminuria in high-risk patients.”

The results are published in the February issue of Hypertension, a journal of the American Heart Association.


Story Source:

The above story is based on materials provided by Medical College of Georgia. Note: Materials may be edited for content and length.


Cite This Page:

Medical College of Georgia. "Urine Protein May Be Present Before Hypertension Diagnosis In At-risk Adolescents." ScienceDaily. ScienceDaily, 29 February 2008. <www.sciencedaily.com/releases/2008/02/080227121837.htm>.
Medical College of Georgia. (2008, February 29). Urine Protein May Be Present Before Hypertension Diagnosis In At-risk Adolescents. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2008/02/080227121837.htm
Medical College of Georgia. "Urine Protein May Be Present Before Hypertension Diagnosis In At-risk Adolescents." ScienceDaily. www.sciencedaily.com/releases/2008/02/080227121837.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins