Featured Research

from universities, journals, and other organizations

New Vaccine Technology Decreases E. Coli In Beef Cattle

Date:
February 29, 2008
Source:
Kansas State University
Summary:
Despite millions of dollars spent on food safety research over the last 10 years, ground beef recalls due to E. coli O157:H7 were higher in 2007 than in 2006, according to researchers from Kansas State University and West Texas A&M University. E. coli O157:H7 has been linked to foodborne illnesses in humans after consuming contaminated beef and produce. A novel vaccine technology to make beef safer.

A new vaccine designed to decrease E. coli shedding in cattle aims to make beef safer.
Credit: Photo by Keith Weller, USDA, ARS.

Despite millions of dollars spent on food safety research over the last 10 years, ground beef recalls due to E. coli O157:H7 were higher in 2007 than in 2006, according to researchers from Kansas State University and West Texas A&M University. E. coli O157:H7 has been linked to foodborne illnesses in humans after consuming contaminated beef and produce.

"We have been studying the effects of a novel vaccine technology to make beef safer," said Dr. Dan Thomson, an associate professor at Kansas State University.

Thomson worked with Dr. Guy Loneragan, West Texas A&M University, and Dr. T.G. Nagaraja, of K-State, to examine the effects of this vaccine on its ability to decrease E. coli shedding in beef cattle.

"We had a decrease in cattle shedding E. coli by 54 percent in our first field study," Thomson said. "However, we increased the amount of SRP exposure in the second field study and decreased the rate of cattle shedding E. coli by 85 percent."

Loneragan said, "This tells us that efficacious interventions that predictably reduce the burden of E. coli O157 on cattle entering packing plants are needed. Successful interventions will reduce the burden of E. coli O157 to a level that is within the capacity of in-plant interventions to handle. If this can be achieved, then tremendous progress toward preventing E. coli O157 from ever getting into ground beef has been made. This vaccine appears to fit this purpose and has great promise."

Thomson and his colleagues studied Siderophore receptor and porin -- SRP -- technology, which was developed by Epitopix, LLC in Willmar, Minn.

"Siderophore receptor and porin proteins are utilized by food borne pathogens like E. coli to acquire iron," Thomson said. "The SRP vaccine technology immunizes animals against these mechanisms and does not allow the bacteria to take up iron. Iron is to bacteria, as oxygen is to humans. Without iron consumption, the bacteria suffocate and can't grow or replicate."

"We conducted a challenge study, a natural infection study and two large pen field studies at commercial feedyards," Thomson said. "All studies showed positive results of this vaccine, making an impact on decreasing not only the number of the cattle shedding the bacteria but also decreasing the concentration of the bacteria being shed."

Super shedder cattle are cattle that shed E. coli in very high concentrations. "Our natural field study showed that the SRP technology vaccine reduces the number of super shedder cattle," Thomson said.

The two large pen feeding studies the team conducted utilized 20 pens and more than 1,200 head of cattle, Thomson said. The first study conducted in 2006 was funded in part by beef and veal producers and importers through their $1-per-head checkoff and was produced for the Cattlemen's Beef Board and state beef councils by the National Cattlemen's Beef Association. The second study was sponsored by Epitopix, LLC in 2007.

The team's findings will be presented at the 2008 Beef Industry Safety Summit in Dallas March 5.


Story Source:

The above story is based on materials provided by Kansas State University. Note: Materials may be edited for content and length.


Cite This Page:

Kansas State University. "New Vaccine Technology Decreases E. Coli In Beef Cattle." ScienceDaily. ScienceDaily, 29 February 2008. <www.sciencedaily.com/releases/2008/02/080227125115.htm>.
Kansas State University. (2008, February 29). New Vaccine Technology Decreases E. Coli In Beef Cattle. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2008/02/080227125115.htm
Kansas State University. "New Vaccine Technology Decreases E. Coli In Beef Cattle." ScienceDaily. www.sciencedaily.com/releases/2008/02/080227125115.htm (accessed September 19, 2014).

Share This



More Plants & Animals News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Elephant Undergoes Surgery in Tbilisi Zoo

Raw: Elephant Undergoes Surgery in Tbilisi Zoo

AP (Sep. 18, 2014) Grand the elephant has successfully undergone surgery to remove a portion of infected tusk at Tbilisi Zoo in Georgia. British veterinary surgeons used an electric drill to extract the infected piece. (Sept. 18) Video provided by AP
Powered by NewsLook.com
Chimp Violence Study Renews Debate On Why They Kill

Chimp Violence Study Renews Debate On Why They Kill

Newsy (Sep. 17, 2014) The study weighs in on a debate over whether chimps are naturally violent or become that way due to human interference in the environment. Video provided by Newsy
Powered by NewsLook.com
Some Tobacco Farmers Thrive Amid Challenges

Some Tobacco Farmers Thrive Amid Challenges

AP (Sep. 16, 2014) The South's tobacco country is surviving, and even thriving in some cases, as demand overseas keeps growers in the fields of one of America's oldest cash crops. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Scientists Given Rare Glimpse of 350-Kilo Colossal Squid

Scientists Given Rare Glimpse of 350-Kilo Colossal Squid

AFP (Sep. 16, 2014) Scientists say a female colossal squid weighing an estimated 350 kilograms (770 lbs) and thought to be only the second intact specimen ever found was carrying eggs when discovered in the Antarctic. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins