Featured Research

from universities, journals, and other organizations

DNA-Guided Nanoparticle Assembly

Date:
March 18, 2008
Source:
DOE/Brookhaven National Laboratory
Summary:
Scientists have developed a new method for controlling the self-assembly of nanometer and micrometer-sized particles. Based on designed DNA shells that coat a particle's surface, the method can be used to manipulate the structure of numerous materials. Such fine-tuning of materials at the molecular level may lead to numerous applications, including cell-targeted systems for drug-delivery and bio-molecular sensing for environmental monitoring or medical applications.

Researchers Matthew Maye, Niels van der Lelie, Oleg Gang, and Dmytro Nykypanchuk.
Credit: Image courtesy of DOE/Brookhaven National Laboratory

Brookhaven Lab scientists have developed a new method for controlling the self-assembly of nanometer and micrometer-sized particles. Based on designed DNA shells that coat a particle's surface, the method can be used to manipulate the structure of numerous materials.

Related Articles


Such fine-tuning of materials at the molecular level may lead to numerous applications, including cell-targeted systems for drug-delivery and bio-molecular sensing for environmental monitoring or medical applications.

"Our method is unique because we attached two types of DNA to the particles' surfaces," said Brookhaven researcher Dmytro Nykypanchuk. " The first type of DNA forms a double helix, while the second type is non-complementary, neutral DNA, so it provides a repulsive force. The addition of the repulsive force allows for regulating the size of particle clusters and the speed of self-assembly with more precision."

In subsequent experiments, the researchers used DNA to guide the creation of three-dimensional, ordered, crystalline structures of nanoparticles. Engineering such 3-D structures is important for producing materials with unique properties that exist at the nanoscale, such as enhanced magnetism and improved catalytic activity.

This new assembly method relies on the attractive forces between complementary strands of DNA, but the scientists also heated the DNA-linked particles, then cooled them back to room temperature. "This 'thermal processing' allows the nanoparticles to unbind, reshuffle, and find more stable binding arrangements," Gang said.

A patent application has been filed for the technology.

This research was presented at The March 2008 American Physical Society Meeting in New Orleans, La., March 10 -14.


Story Source:

The above story is based on materials provided by DOE/Brookhaven National Laboratory. Note: Materials may be edited for content and length.


Cite This Page:

DOE/Brookhaven National Laboratory. "DNA-Guided Nanoparticle Assembly." ScienceDaily. ScienceDaily, 18 March 2008. <www.sciencedaily.com/releases/2008/03/080313202938.htm>.
DOE/Brookhaven National Laboratory. (2008, March 18). DNA-Guided Nanoparticle Assembly. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2008/03/080313202938.htm
DOE/Brookhaven National Laboratory. "DNA-Guided Nanoparticle Assembly." ScienceDaily. www.sciencedaily.com/releases/2008/03/080313202938.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Matter & Energy News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Navy Unveils Robot Fish

Navy Unveils Robot Fish

Reuters - Light News Video Online (Dec. 18, 2014) The U.S. Navy unveils an underwater device that mimics the movement of a fish. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
3D Printed Cookies Just in Time for Christmas

3D Printed Cookies Just in Time for Christmas

Reuters - Innovations Video Online (Dec. 18, 2014) A tech company in Spain have combined technology with cuisine to develop the 'Foodini', a 3D printer designed to print the perfect cookie for Santa. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
First Etihad Superjumbo Flight in December

First Etihad Superjumbo Flight in December

AFP (Dec. 18, 2014) The first flight of Etihad Airways' long-awaited Airbus A380 superjumbo will take place later in December, the Abu Dhabi carrier said Thursday, also announcing its first Boeing 787 Dreamliner route. Duration: 01:09 Video provided by AFP
Powered by NewsLook.com
Ford Expands Air Bag Recall Nationwide

Ford Expands Air Bag Recall Nationwide

Newsy (Dec. 18, 2014) The automaker added 447,000 vehicles to its recall list, bringing the total to more than 502,000. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins