Featured Research

from universities, journals, and other organizations

DNA-Guided Nanoparticle Assembly

Date:
March 18, 2008
Source:
DOE/Brookhaven National Laboratory
Summary:
Scientists have developed a new method for controlling the self-assembly of nanometer and micrometer-sized particles. Based on designed DNA shells that coat a particle's surface, the method can be used to manipulate the structure of numerous materials. Such fine-tuning of materials at the molecular level may lead to numerous applications, including cell-targeted systems for drug-delivery and bio-molecular sensing for environmental monitoring or medical applications.

Researchers Matthew Maye, Niels van der Lelie, Oleg Gang, and Dmytro Nykypanchuk.
Credit: Image courtesy of DOE/Brookhaven National Laboratory

Brookhaven Lab scientists have developed a new method for controlling the self-assembly of nanometer and micrometer-sized particles. Based on designed DNA shells that coat a particle's surface, the method can be used to manipulate the structure of numerous materials.

Related Articles


Such fine-tuning of materials at the molecular level may lead to numerous applications, including cell-targeted systems for drug-delivery and bio-molecular sensing for environmental monitoring or medical applications.

"Our method is unique because we attached two types of DNA to the particles' surfaces," said Brookhaven researcher Dmytro Nykypanchuk. " The first type of DNA forms a double helix, while the second type is non-complementary, neutral DNA, so it provides a repulsive force. The addition of the repulsive force allows for regulating the size of particle clusters and the speed of self-assembly with more precision."

In subsequent experiments, the researchers used DNA to guide the creation of three-dimensional, ordered, crystalline structures of nanoparticles. Engineering such 3-D structures is important for producing materials with unique properties that exist at the nanoscale, such as enhanced magnetism and improved catalytic activity.

This new assembly method relies on the attractive forces between complementary strands of DNA, but the scientists also heated the DNA-linked particles, then cooled them back to room temperature. "This 'thermal processing' allows the nanoparticles to unbind, reshuffle, and find more stable binding arrangements," Gang said.

A patent application has been filed for the technology.

This research was presented  at The March 2008 American Physical Society Meeting in New Orleans, La., March 10 -14.


Story Source:

The above story is based on materials provided by DOE/Brookhaven National Laboratory. Note: Materials may be edited for content and length.


Cite This Page:

DOE/Brookhaven National Laboratory. "DNA-Guided Nanoparticle Assembly." ScienceDaily. ScienceDaily, 18 March 2008. <www.sciencedaily.com/releases/2008/03/080313202938.htm>.
DOE/Brookhaven National Laboratory. (2008, March 18). DNA-Guided Nanoparticle Assembly. ScienceDaily. Retrieved January 30, 2015 from www.sciencedaily.com/releases/2008/03/080313202938.htm
DOE/Brookhaven National Laboratory. "DNA-Guided Nanoparticle Assembly." ScienceDaily. www.sciencedaily.com/releases/2008/03/080313202938.htm (accessed January 30, 2015).

Share This


More From ScienceDaily



More Matter & Energy News

Friday, January 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Tesla 'Insane Mode' Gives Unsuspecting Passengers the Ride of Their Life

Tesla 'Insane Mode' Gives Unsuspecting Passengers the Ride of Their Life

RightThisMinute (Jan. 29, 2015) — If your car has an "Insane Mode" then you know it&apos;s fast. Well, these unsuspecting passengers were in for one insane ride when they hit the button. Tesla cars are awesome. Video provided by RightThisMinute
Powered by NewsLook.com
Now Bill Gates Is 'Concerned' About Artificial Intelligence

Now Bill Gates Is 'Concerned' About Artificial Intelligence

Newsy (Jan. 29, 2015) — Bill Gates joins the list of tech moguls scared of super-intelligent machines. He says more people should be concerned, but why? Video provided by Newsy
Powered by NewsLook.com
Senate Passes Bill for Keystone XL Pipeline

Senate Passes Bill for Keystone XL Pipeline

AP (Jan. 29, 2015) — The Republican-controlled Senate has passed a bipartisan bill approving construction of the Keystone XL oil pipeline. (Jan. 29) Video provided by AP
Powered by NewsLook.com
Two Stunt Pilots Perform Incredibly Close Flyby

Two Stunt Pilots Perform Incredibly Close Flyby

Rumble (Jan. 29, 2015) — Two pilots from &apos;Escuadrilla Argentina de Acrobacia Aιrea&apos; perform an incredibly low altitude flyby stunt during a recent show exhibition in Argentina. Check it out! Video provided by Rumble
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins