Featured Research

from universities, journals, and other organizations

Coffee May Protect Against Breast Cancer, Study Shows

Date:
April 25, 2008
Source:
Lund University
Summary:
Depending on which variant of a certain gene a woman has, a coffee consumption rate of at least two-three cups a day can either reduce the total risk of developing breast cancer or delay the onset of cancer, according to new research. The effect of coffee is related to estrogens, female sex hormones. Certain metabolic products of these hormones are known to be carcinogenic, and various components of coffee can alter the metabolism so that a woman acquires a better configuration of various estrogens. What's more, coffee contains caffeine, which also hampers the growth of cancer cells.

Depending on which variant of a certain gene a woman has, a coffee consumption rate of at least two-three cups a day can either reduce the total risk of developing breast cancer or delay the onset of cancer. This is shown in new research from Lund University and Malmö University in Sweden.

The effect of coffee is related to estrogens, female sex hormones. Certain metabolic products of these hormones are known to be carcinogenic, and various components of coffee can alter the metabolism so that a woman acquires a better configuration of various estrogens. What’s more, coffee contains caffeine, which also hampers the growth of cancer cells.

The cancer researcher Helena Jernström and her associates have studied the coffee-drinking habits of nearly 460 breast cancer patients being treated in Lund. The results show that the effect of coffee varies depending on which variant the women have of a gene called CYP1A2, which codes for an enzyme that metabolizes both estrogen and coffee. Half of the women had a variant called A/A, while the others had either A/C or C/C.

“Those women who had one of the C variants, and who had drunk at least three cups of coffee a day, developed breast cancer considerably more seldom than women with the A/A variant with the same coffee consumption. Their cancer risk was only two thirds of that of the other women.

A/A women who had drunk two or more cups of coffee a day received more ambiguous help from their coffee consumption. On the one hand, their cancer appeared considerably later than among women who had seldom or never drunk coffee at a mean age of 58 years instead of 48 years, unless they had taken hormone replacement therapy for menopausal symptoms, says Helena Jernström.. On the other hand, nearly 15 percent of these women had estrogen-insensitive (ER negative) tumors, which are more difficult to treat.

“The majority nevertheless had estrogen-sensitive and more readily treated tumors. And women who develop breast cancer at a higher age often do better than those who get it earlier in life,” says Helena Jernström.

She stresses, however, that it is too early to make any dietary recommendations regarding coffee consumption.

“This is new information that needs to be corroborated in other studies before we can issue any recommendations. If coffee does in fact provide some protection against breast cancer, then women in such a coffee-drinking country as Sweden ought to have fewer cases of cancer than other countries. This is also the case, at least compared with the U.S. There the proportion of breast cancer cases in the population is considerably higher, and there people drink both more decaffeinated coffee and less coffee in general.”

These research findings are published in the journal Cancer Epidemiology, Biomarkers and Prevention, with doctoral student Erika Bågeman as lead author.


Story Source:

The above story is based on materials provided by Lund University. Note: Materials may be edited for content and length.


Cite This Page:

Lund University. "Coffee May Protect Against Breast Cancer, Study Shows." ScienceDaily. ScienceDaily, 25 April 2008. <www.sciencedaily.com/releases/2008/04/080424115324.htm>.
Lund University. (2008, April 25). Coffee May Protect Against Breast Cancer, Study Shows. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2008/04/080424115324.htm
Lund University. "Coffee May Protect Against Breast Cancer, Study Shows." ScienceDaily. www.sciencedaily.com/releases/2008/04/080424115324.htm (accessed August 22, 2014).

Share This




More Health & Medicine News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) — An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) — Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) — Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) — It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins