Featured Research

from universities, journals, and other organizations

Smokers With Advanced Colon Cancer May Face Higher Odds Of Disease Recurrence

Date:
June 2, 2008
Source:
Dana-Farber Cancer Institute
Summary:
People with advanced colon cancer who have smoked cigarettes or used other tobacco products for many years may have an increased risk that their colon cancer will return, according to research by Dana-Farber Cancer Institute scientists.

People with advanced colon cancer who have smoked cigarettes or used other tobacco products for many years may have an increased risk that their colon cancer will return, according to research by Dana-Farber Cancer Institute scientists to be presented at the annual meeting of the American Society of Clinical Oncology (ASCO), May 30-June 3, in Chicago.

Based on data from 965 patients treated for stage III colon cancer, investigators found the chances of recurrence or death up to 22 percent higher in patients with a 20 or more pack year history (calculated by number of years smoking times packs per day) than in those who had never smoked. Smoking history prior to age 30 was particularly harmful for subjects that developed colon cancer years later. Patients who smoked 12 pack years or more before age 30 and developed colon cancer later in life had a statistically significant 37 percent increase in recurrence or death compared to nonsmokers.

"After controlling for other factors that may influence the risk of colon cancer recurrence or death, this study highlights further risk of cancer recurrence in individuals who have a higher lifetime total use of cigarettes than never smokers," said lead author Nadine Jackson, MD, MPH, of Dana-Farber.

Although tobacco use can increase people's initial risk of colon cancer, little is known about the short- or long-term effects of such use on disease recurrence. The current study is part of an effort to explore that issue.

Participants in the study reported their tobacco use on questionnaires filled out during and six months after their treatment. Forty-five percent were identified as past smokers, 9 percent as current smokers, and 46 percent as never smokers.

The study's co-authors are Jeffrey Meyerhardt, MD, MPH, Charles Fuchs, MD, MPH, and Robert Mayer, MD, of Dana-Farber, Boston; Donna Niedzwiecki, PhD, and Donna Hollis, PhD, of the Cancer and Leukemia Group B, Durham, N.C.; and Leonard Saltz, MD, of Memorial Sloan-Kettering Cancer Center, New York.


Story Source:

The above story is based on materials provided by Dana-Farber Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Dana-Farber Cancer Institute. "Smokers With Advanced Colon Cancer May Face Higher Odds Of Disease Recurrence." ScienceDaily. ScienceDaily, 2 June 2008. <www.sciencedaily.com/releases/2008/05/080530095421.htm>.
Dana-Farber Cancer Institute. (2008, June 2). Smokers With Advanced Colon Cancer May Face Higher Odds Of Disease Recurrence. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2008/05/080530095421.htm
Dana-Farber Cancer Institute. "Smokers With Advanced Colon Cancer May Face Higher Odds Of Disease Recurrence." ScienceDaily. www.sciencedaily.com/releases/2008/05/080530095421.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins