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Schistosomes, Hookworm And Trichuris Infections Synergize To Increase The Risk Of Anemia

Date:
June 4, 2008
Source:
Public Library of Science
Summary:
New research provides evidence that the risk of anemia is amplified in children simultaneously infected with hookworm and schistosomes or hookworm and trichuris, when compared to the sum of risks for children with singular infections.

New research provides evidence that the risk of anemia is amplified in children simultaneously infected with hookworm and schistosomes or hookworm and trichuris, when compared to the sum of risks for children with singular infections.

Amara Ezeamama and colleagues conducted this study in 507 school-age children from helminth-endemic villages in The Philippines, to determine whether co- infections of hookworm, schistosomes and trichuris in polyparasitized individuals magnified the risk of becoming anemic beyond the sum of risks associated with individual infections.

It is common in many tropical developing countries for individuals to be infected with several parasites at the same time. Despite this widespread phenomenon, the functional and health consequences of multiple infections for parasite-associated morbidity such as anemia are not clearly understood.

Previous work by these scientists suggested that low-intensity polyparasitic infections were associated with higher odds of anemia among school-age children relative to uninfected children or children with one low infection. This study goes further to specifically evaluate the type and extent of biological interactions between helminth species in polyparasitized individuals.

Results from this research suggest that combined treatment for some helminth species and schistosomes could yield greater than additive benefits for reducing the burden of anemia in helminth-endemic areas. However, more studies to understand the full range of interactions between parasite species in their joint effects on helminth-associated morbidities will be necessary to better predict the impact of wide-scale public health intervention.



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The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ezeamama et al. The Synergistic Effect of Concomitant Schistosomiasis, Hookworm, and Trichuris Infections on Children's Anemia Burden. PLoS Neglected Tropical Diseases, 2008; 2 (6): e245 DOI: 10.1371/journal.pntd.0000245

Cite This Page:

Public Library of Science. "Schistosomes, Hookworm And Trichuris Infections Synergize To Increase The Risk Of Anemia." ScienceDaily. ScienceDaily, 4 June 2008. <www.sciencedaily.com/releases/2008/06/080604074936.htm>.
Public Library of Science. (2008, June 4). Schistosomes, Hookworm And Trichuris Infections Synergize To Increase The Risk Of Anemia. ScienceDaily. Retrieved August 29, 2014 from www.sciencedaily.com/releases/2008/06/080604074936.htm
Public Library of Science. "Schistosomes, Hookworm And Trichuris Infections Synergize To Increase The Risk Of Anemia." ScienceDaily. www.sciencedaily.com/releases/2008/06/080604074936.htm (accessed August 29, 2014).

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