Featured Research

from universities, journals, and other organizations

Age At Puberty Linked To Mother's Prenatal Diet

Date:
June 17, 2008
Source:
The Endocrine Society
Summary:
A high-fat diet during pregnancy and nursing may lead to the child having an early onset of puberty and subsequent adulthood obesity, according to a new animal study.

A high-fat diet during pregnancy and nursing may lead to the child having an early onset of puberty and subsequent adulthood obesity, according to a new animal study. The results were presented June 16, at The Endocrine Society's 90th Annual Meeting in San Francisco.

An early first menstrual period, often used as a marker for early-onset puberty in girls is a risk factor for obesity, insulin resistance, teenage depression, and breast cancer in adulthood, said Deborah Sloboda, PhD, lead author of the study. She is a researcher at The Liggins Institute of the University of Auckland in New Zealand.

"Other research suggests that a combination of prenatal and postnatal influences in girls can affect the onset of menarche [menstruation]," Sloboda said.

She and her colleagues therefore studied how prenatal nutrition and nutrition during childhood interact to alter reproductive maturation. The study was done in rats.

The investigators fed pregnant rats a high-fat diet throughout pregnancy and lactation (breastfeeding). Control rats received a regular diet of rat chow. After weaning from their mother's milk, the offspring ate either regular chow or a high-fat diet. Onset of puberty was determined using established techniques. The researchers also evaluated the offspring as adults in regard to body fat composition and blood levels of sex hormones.

The onset of puberty was much earlier in all rats whose mothers had a high-fat diet, compared with the offspring of controls that ate a regular diet, the study showed. Controls' offspring that ate a high-fat diet after weaning also entered puberty early. The combination of a high-fat maternal diet--that is, inside the mother's womb--and a high-fat diet after birth did not make the early-onset puberty any earlier, Sloboda said.

"This might suggest that the fetal environment in high fat fed mothers plays a greater role in determining pubertal onset than childhood nutrition," she said.

Later in life, rats born to mothers fed a high-fat diet had a higher amount of body fat than controls did, even if they ate a regular diet while young.

Among the adult rats that had a maternal high-fat diet, the study showed alterations in sex hormones, including increased levels of the ovarian hormone progesterone in females.

"Maternal high-fat nutrition may influence reproductive maturation and reproductive capacity in adult offspring," Sloboda said.

The Health Research Council of New Zealand, National Research Centre for Growth and Development, and Maurice and Phyllis Paykel Trust in New Zealand all supported this research.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Cite This Page:

The Endocrine Society. "Age At Puberty Linked To Mother's Prenatal Diet." ScienceDaily. ScienceDaily, 17 June 2008. <www.sciencedaily.com/releases/2008/06/080616151748.htm>.
The Endocrine Society. (2008, June 17). Age At Puberty Linked To Mother's Prenatal Diet. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2008/06/080616151748.htm
The Endocrine Society. "Age At Puberty Linked To Mother's Prenatal Diet." ScienceDaily. www.sciencedaily.com/releases/2008/06/080616151748.htm (accessed April 17, 2014).

Share This



More Health & Medicine News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com
Formerly Conjoined Twins Released From Dallas Hospital

Formerly Conjoined Twins Released From Dallas Hospital

Newsy (Apr. 16, 2014) Conjoined twins Emmett and Owen Ezell were separated by doctors in August. Now, nearly nine months later, they're being released from the hospital. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins