Featured Research

from universities, journals, and other organizations

Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis

Date:
June 19, 2008
Source:
Cedars-Sinai Medical Center
Summary:
On Nov. 26, 2007, doctors at the Cedars-Sinai Heart Institute performed the first "transcatheter" minimally invasive replacement of an aortic heart valve in the western United States, using the SAPIEN transcatheter aortic heart valve developed by Edwards Lifesciences Corp. Cedars-Sinai is one of 15 centers participating in a pivotal clinical trial (the PARTNER trial) of the device.

On Nov. 26, 2007, doctors at the Cedars-Sinai Heart Institute performed the first "transcatheter" minimally invasive replacement of an aortic heart valve in the western United States, using the SAPIEN transcatheter aortic heart valve developed by Edwards Lifesciences Corp. Cedars-Sinai is one of 15 centers participating in a pivotal clinical trial (the PARTNER trial) of the device, and is the leading enroller in the nation.

The aortic valve controls blood flow from the heart's main pumping chamber into the body's largest arterial trunk. Stenosis (narrowing) at the valve reduces the outward flow of oxygenated blood and leads to congestive heart failure as the organ stretches to accommodate a greater-than-normal volume of blood.

While replacement mechanical or biological valves can be implanted, this is traditionally done via open-heart surgery. Many patients with aortic stenosis cannot be treated because they are not considered good candidates for surgery.

Transcatheter aortic valve replacement is accomplished in much the way blocked heart arteries are opened with balloon angioplasty and stents. A tube (catheter) containing a compressed balloon is inserted into a blood vessel at the groin and threaded up to the heart. The balloon is placed inside the damaged valve and inflated to open the narrowed area.

A "stent valve" consisting of bovine pericardial tissue and a stainless steel frame is then put into position and the balloon is inflated to expand the valve and press it into the calcified tissue on the artery wall. The balloon catheter is then removed, leaving the new, functioning valve in place.


Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis." ScienceDaily. ScienceDaily, 19 June 2008. <www.sciencedaily.com/releases/2008/06/080619100411.htm>.
Cedars-Sinai Medical Center. (2008, June 19). Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2008/06/080619100411.htm
Cedars-Sinai Medical Center. "Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis." ScienceDaily. www.sciencedaily.com/releases/2008/06/080619100411.htm (accessed April 17, 2014).

Share This



More Health & Medicine News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com
Formerly Conjoined Twins Released From Dallas Hospital

Formerly Conjoined Twins Released From Dallas Hospital

Newsy (Apr. 16, 2014) Conjoined twins Emmett and Owen Ezell were separated by doctors in August. Now, nearly nine months later, they're being released from the hospital. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins