Featured Research

from universities, journals, and other organizations

Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis

Date:
June 20, 2008
Source:
Cedars-Sinai Medical Center
Summary:
On Nov. 26, 2007, doctors at the Cedars-Sinai Heart Institute performed the first "transcatheter" minimally invasive replacement of an aortic heart valve in the western United States, using the Edwards SAPIEN transcatheter aortic heart valve developed by Edwards Lifesciences Corp.

On Nov. 26, 2007, doctors at the Cedars-Sinai Heart Institute performed the first "transcatheter" minimally invasive replacement of an aortic heart valve in the western United States, using the Edwards SAPIEN transcatheter aortic heart valve developed by Edwards Lifesciences Corp. Cedars-Sinai is one of 16 centers participating in a pivotal clinical trial (the PARTNER trial) of the device, and is the only site currently recruiting on the West Coast.

Related Articles


The aortic valve controls blood flow from the heart's main pumping chamber into the body's largest arterial trunk. Stenosis (narrowing) at the valve reduces the outward flow of oxygenated blood and leads to congestive heart failure as the organ stretches to accommodate a greater-than-normal volume of blood.

While replacement mechanical or biological valves can be implanted, this is traditionally done via open-heart surgery. Many patients with aortic stenosis cannot be treated because they are not considered good candidates for surgery.

Transcatheter aortic valve replacement is accomplished in much the way blocked heart arteries are opened with balloon angioplasty and stents. A tube (catheter) containing a compressed balloon is inserted into a blood vessel at the groin and threaded up to the heart. The balloon is placed inside the damaged valve and inflated to open the narrowed area. A "stent valve" consisting of bovine pericardial tissue and a stainless steel frame is then placed on the catheter, threaded up to the heart, put into position and the balloon is inflated to expand the valve and press it into the calcified tissue on the artery wall. The balloon catheter is then removed, leaving the new, functioning valve in place.


Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis." ScienceDaily. ScienceDaily, 20 June 2008. <www.sciencedaily.com/releases/2008/06/080620195515.htm>.
Cedars-Sinai Medical Center. (2008, June 20). Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2008/06/080620195515.htm
Cedars-Sinai Medical Center. "Clinical Trial Of Nonsurgical Intervention For Aortic Valve Stenosis." ScienceDaily. www.sciencedaily.com/releases/2008/06/080620195515.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins