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Uncertainties Prevail Over Human Health Benefits Of Polyphenols

Date:
August 25, 2008
Source:
American Chemical Society
Summary:
Despite scores of studies documenting the effects of healthful plant nutrients called polyphenols in protecting nerves from damage, it would be "unwise" to assume that the same protective effects occur for Alzheimer's disease (AD) and other human disorders, a new report concludes.

Despite scores of studies documenting the effects of healthful plant nutrients called polyphenols in protecting nerves from damage, it would be "unwise" to assume that the same protective effects occur for Alzheimer's disease (AD) and other human disorders, a new report concludes.

In the report, Charles Ramassamy and colleagues in Canada analyzed the results of more than 200 laboratory and animal studies on these materials, found in fruits, vegetables, wine, chocolate, coffee, tea, and other foods.

They found abundant evidence that polyphenols do, indeed, protect nerves from the kind of damage that occurs in AD and other chronic brain disorders.

The researchers concluded, however, that "it is not at all clear whether these compounds reach the brain in sufficient concentrations and in a biologically active form to exert beneficial effects."

Resolving those uncertainties will take years of additional research, they say in the report, which includes a list of the 50 foods containing the highest amounts of polyphenols.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Singh et al. Challenges for Research on Polyphenols from Foods in Alzheimer’s Disease: Bioavailability, Metabolism, and Cellular and Molecular Mechanisms. Journal of Agricultural and Food Chemistry, 2008; 56 (13): 4855 DOI: 10.1021/jf0735073

Cite This Page:

American Chemical Society. "Uncertainties Prevail Over Human Health Benefits Of Polyphenols." ScienceDaily. ScienceDaily, 25 August 2008. <www.sciencedaily.com/releases/2008/07/080707092055.htm>.
American Chemical Society. (2008, August 25). Uncertainties Prevail Over Human Health Benefits Of Polyphenols. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2008/07/080707092055.htm
American Chemical Society. "Uncertainties Prevail Over Human Health Benefits Of Polyphenols." ScienceDaily. www.sciencedaily.com/releases/2008/07/080707092055.htm (accessed April 20, 2014).

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