Featured Research

from universities, journals, and other organizations

New Method Identifies Genes Affecting Health In Fraction Of A Second

Date:
July 11, 2008
Source:
University of Southampton
Summary:
A new tool which makes it possible to extract information about an individual's health from genotypes in a fraction of a second, has just been developed.

A new tool which makes it possible to extract information about an individual's health from genotypes in a fraction of a second, has been developed by an academic at the University of Southampton.

Professor Joao Marques-Silva, at the University's School of Electronics and Computer Science and collaborators have developed a new approach to the process of inferring haplotype information from genotype data.

A haplotype can be defined as a group of alleles of one or more genes on a single chromosome that are closely enough linked to be inherited usually as a unit and a genotype refers to the combination of alleles inherited from both parents.

According to Professor Marques-Silva, the current method of extracting haplotypes from genotype data is based on statistical approaches, which can take a long time to compute.

Professor Marques-Silva and collaborators approached this scenario by taking the Haplotype Inference by Pure Parsimony (HIPP), a solution that minimises the total number of distinct haplotypes used, and developed new algorithms which they applied to achieve faster results.

'Biologists have been using these statistical approaches for a long time and may not be open to change,' he said. 'However, these methods can take days, even months to terminate, whereas our approach produces an almost instant result.'

Further research is being carried out currently by Professor Marques-Silva and collaborators to validate this new method and to prove that it could replace statistical methods in a number of settings.

'This is the biggest development that we have made in this field so far,' said Professor Marques-Silva. 'It remains to be seen whether biologists will use this instead of existing techniques.'


Story Source:

The above story is based on materials provided by University of Southampton. Note: Materials may be edited for content and length.


Journal Reference:

  1. Lynce et al. Boosting Haplotype Inference with Local Search. Constraints, 2008; 13 (1-2): 155 DOI: 10.1007/s10601-007-9035-7

Cite This Page:

University of Southampton. "New Method Identifies Genes Affecting Health In Fraction Of A Second." ScienceDaily. ScienceDaily, 11 July 2008. <www.sciencedaily.com/releases/2008/07/080709124848.htm>.
University of Southampton. (2008, July 11). New Method Identifies Genes Affecting Health In Fraction Of A Second. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2008/07/080709124848.htm
University of Southampton. "New Method Identifies Genes Affecting Health In Fraction Of A Second." ScienceDaily. www.sciencedaily.com/releases/2008/07/080709124848.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins