Featured Research

from universities, journals, and other organizations

Regular Salmeterol For Asthma: More Evidence Of Long-term Problems

Date:
July 15, 2008
Source:
Wiley-Blackwell
Summary:
People with asthma who regularly use salmeterol are at a greater risk of non-fatal serious adverse events than those using placebos. This conclusion was arrived at by a team of Cochrane researchers who drew together data from 26 trials involving 62,630 patients.

People with asthma who regularly use salmeterol are at a greater risk of non-fatal serious adverse events than those using placebos. This conclusion was arrived at by a team of Cochrane Researchers who drew together data from 26 trials involving 62,630 patients.

Related Articles


The researchers found that over a four to six month period, for every thousand people treated for asthma there were 45 who suffered a serious adverse event on regular salmeterol, compared to only 40 if a placebo inhaler was given.

Salmeterol is a long-acting beta2-agonist. It is inhaled by people with asthma twice daily, and relieves symptoms for up to 12 hours. It is generally recommended for use along with corticosteroid inhalers (also known as preventer inhalers).

Over the last decade some researchers and practitioners have expressed anxieties that although salmeterol can relieve asthma symptoms, it could cause long-term problems.

"We found that the biggest increase in risk was seen in people with asthma who were not taking inhaled corticosteroids; however, there is no guarantee that inhaled corticosteroids abolish the risk all together," says lead researcher Christopher Cates who works in Community Health Sciences at St George's, London, UK.

The authors recommend that people should follow the manufacturer's advice not to increase the dose of salmeterol during an exacerbation. Furthermore regular salmeterol should not be used as an alternative to inhaled corticosteroids. Benefits and risks both need to be considered before embarking on long term treatment with regular salmeterol.

Work is currently in progress on a similar assessment of formoterol (another long-acting beta2-agonist).


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "Regular Salmeterol For Asthma: More Evidence Of Long-term Problems." ScienceDaily. ScienceDaily, 15 July 2008. <www.sciencedaily.com/releases/2008/07/080715204837.htm>.
Wiley-Blackwell. (2008, July 15). Regular Salmeterol For Asthma: More Evidence Of Long-term Problems. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2008/07/080715204837.htm
Wiley-Blackwell. "Regular Salmeterol For Asthma: More Evidence Of Long-term Problems." ScienceDaily. www.sciencedaily.com/releases/2008/07/080715204837.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com
Toddlers Drinking Coffee? Why You Shouldn't Share Your Joe

Toddlers Drinking Coffee? Why You Shouldn't Share Your Joe

Newsy (Mar. 5, 2015) A survey of Boston mothers and toddlers found that 15 percent of two-year-olds drink coffee and 2.5 percent of 1-year-olds. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins