Featured Research

from universities, journals, and other organizations

Guiding Lasers To Their Target

Date:
August 6, 2008
Source:
American Institute of Physics
Summary:
Like most treatments, laser therapy can benefit from image guidance. A Houston-based company has developed an MRI-guided system that has been tested and is now FDA-approved.

Like most treatments, laser therapy can benefit from image guidance. A Houston-based company has developed an MRI-guided system that has been tested and is now FDA-approved.

Laser induced thermal therapy (LITT) destroys unhealthy tissue, like cancer, with the intense heat supplied from a laser. The laser light is channeled through an optical fiber that can be inserted practically anywhere in the body. One of the biggest challenges in LITT is that the target cannot get too hot, otherwise it will char - thus preventing further laser light from penetrating into the tissue.

To avoid this, physicians have traditionally measured the temperature at some point near the target using a thermometer-like probe. But real-time imaging could provide a non-invasive means to monitor the temperature throughout the target region. In particular, MRI provides a sensitive temperature probe. The frequency of the MRI signal, which depends on the magnetic properties of water molecules, shifts as the temperature of the corresponding tissue changes.

Using this effect, Visualase, Inc., has developed a closed-loop MRI guided LITT system that provides the user with a temperature map of the target region and calculates the corresponding dose (i.e. the likelihood that cells in some region will die from the applied heat). If nearby healthy tissue is receiving too much heat, or if the temperature is approaching the charring temperature, the user can respond by changing the laser power or shutting it off, which helps to increase both the safety and efficacy of the procedure.

Trials of the system were independently performed on canines by R. Jason Stafford from the University of Texas M.D. Anderson Cancer Center, and his collaborators. Several LITT lesions were made in the brain, spine and prostate with MRI guidance. The results showed that the machine's calculated dose matched up well with a post-operation assessment. Initial safety studies have also been performed in human patients and the device has recently received FDA approval. Stafford thinks MRI-guided LITT will provide a less invasive alternative to conventional surgery. He is currently working to improve the real-time targeting and heat delivery.

The research was described in the talk, "Closed-Loop Guidance of Laser Induced Thermal Therapy Using MRI," presented July 31, 2008 at the 50th meeting of the American Association of Physicists in Medicine.


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Cite This Page:

American Institute of Physics. "Guiding Lasers To Their Target." ScienceDaily. ScienceDaily, 6 August 2008. <www.sciencedaily.com/releases/2008/08/080805160316.htm>.
American Institute of Physics. (2008, August 6). Guiding Lasers To Their Target. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2008/08/080805160316.htm
American Institute of Physics. "Guiding Lasers To Their Target." ScienceDaily. www.sciencedaily.com/releases/2008/08/080805160316.htm (accessed September 16, 2014).

Share This



More Matter & Energy News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Manufacturer Prints 3-D Car In Record Time

Manufacturer Prints 3-D Car In Record Time

Newsy (Sep. 15, 2014) — Automobile manufacturer Local Motors created a drivable electric car using a 3-D printer. Printing the body only took 44 hours. Video provided by Newsy
Powered by NewsLook.com
Refurbished New York Subway Tunnel Unveiled After Sandy Damage

Refurbished New York Subway Tunnel Unveiled After Sandy Damage

Reuters - US Online Video (Sep. 15, 2014) — New York officials unveil subway tunnels that were refurbished after Superstorm Sandy. Nathan Frandino reports. Video provided by Reuters
Powered by NewsLook.com
Frustration As Drone Industry Outpaces Regulation In U.S.

Frustration As Drone Industry Outpaces Regulation In U.S.

Newsy (Sep. 14, 2014) — U.S. firms worry they’re falling behind in the marketplace as the FAA considers how to regulate commercial drones. Video provided by Newsy
Powered by NewsLook.com
Smart Gun Innovators Fear Backlash From Gun Rights Advocates

Smart Gun Innovators Fear Backlash From Gun Rights Advocates

Newsy (Sep. 14, 2014) — Winners of a contest for smart gun design are asking not to be named after others in the industry received threats for marketing similar products. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins