Featured Research

from universities, journals, and other organizations

Cell Removal Technique Could Lead To Cheaper Drugs

Date:
August 27, 2008
Source:
University of Edinburgh
Summary:
Costly drugs to treat conditions such as cancer and arthritis could be manufactured more cheaply with a new technique. Researchers have pioneered a simple way to remove dead cells from cell cultures used to make protein-based drugs, which are increasingly prescribed to treat a range of illnesses.

Costly drugs to treat conditions such as cancer and arthritis could be manufactured more cheaply with a new technique.

Researchers at the University of Edinburgh have pioneered a simple way to remove dead cells from cell cultures used to make protein-based drugs, which are increasingly prescribed to treat a range of illnesses.

Such medicines are expensive to make, with high costs resulting from the time-consuming and labour-intensive nature of developing them in cell culture.

Scientists have streamlined this process using magnetic beads coated with special antibodies that bind to dead cells without harming the remaining healthy cells. A magnet is then used to draw the dead cells out, leaving the living cells to produce beneficial proteins more effectively.

Professor Chris Gregory, of the University's Centre for Inflammation Research, said: "We are essentially mimicking what happens in the body when scavenger cells remove dead and abnormal cells. If the dead cells are not removed, then this affects how healthy cells behave.

"Not only will this make the production of drugs more efficient, but it will also streamline research into new medicines which use cell culture."

A spin-off company, Immunosolv, has been formed to market the technology following support through Scottish Enterprise's Proof of Concept Programme and a SMART award.

Researchers have found that removing dead cells can increase productivity of cell cultures by more than 100 per cent. The method replaces lengthy and potentially damaging methods of cell removal, such as spinning cultures around at high speeds, which can traumatise healthy cells, and could also have implications for vaccine development and stem cell research.


Story Source:

The above story is based on materials provided by University of Edinburgh. Note: Materials may be edited for content and length.


Cite This Page:

University of Edinburgh. "Cell Removal Technique Could Lead To Cheaper Drugs." ScienceDaily. ScienceDaily, 27 August 2008. <www.sciencedaily.com/releases/2008/08/080826093302.htm>.
University of Edinburgh. (2008, August 27). Cell Removal Technique Could Lead To Cheaper Drugs. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2008/08/080826093302.htm
University of Edinburgh. "Cell Removal Technique Could Lead To Cheaper Drugs." ScienceDaily. www.sciencedaily.com/releases/2008/08/080826093302.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins