Featured Research

from universities, journals, and other organizations

'Lab On A Chip' Improves Success Of In Vitro Fertilization

Date:
September 4, 2008
Source:
American Chemical Society
Summary:
In a finding that could boost the success rate of in vitro fertilization (IVF), researchers report development of a tiny "lab on a chip" to evaluate the fitness of embryos harvested for transfer.

Scientists could improve the success rate of in vitro fertilization using a "lab on a chip" to study embryos. Above is a mouse embryo at the fifth day of development cultured in a 1 microliter droplet.
Credit: Mark Johnson and Amanda Pennington

In a finding that could boost the success rate of in vitro fertilization (IVF), researchers report development of a tiny "lab on a chip" to evaluate the fitness of embryos harvested for transfer.

Researchers describe the method as faster, easier, and more reliable than conventional embryo selection methods.

In the new study, Todd Thorsen and colleagues note that the current method for evaluating an embryo's fitness for IVF involves microscopic examination of the embryo's physical characteristics, such as cell shape, which is time-consuming and unreliable.

Almost 130,000 women undergo IVF procedures each year in the U.S. alone, but the procedure has only a 30 percent success rate. To boost IVF success, doctors often transfer more than one embryo to the uterus, which can lead to multiple births and increases the pregnancy risks to mother and child. A better, more targeted method of embryo selection is needed, the researchers say.

The scientists describe development of a so-called microfluidic chip, about the size of a quarter. It is intended to automatically analyze the health of embryos intended for transplant by measuring how the embryo alters key nutrients in the tissue culture medium used to nurture embryos.

In laboratory studies, the researchers collected fluids surrounding 10 mouse embryos and added the fluids to the computer-controlled chip for analysis. They showed that the device could quickly (in minutes instead of hours) and accurately measure the nutrient content of the sample fluids.

Besides improving the quality of embryos chosen for IVF, the system could ultimately cut costs associated with the procedure, the scientists say.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Urbanski et al. Noninvasive Metabolic Profiling Using Microfluidics for Analysis of Single Preimplantation Embryos. Analytical Chemistry, 2008; 80 (17): 6500 DOI: 10.1021/ac8010473

Cite This Page:

American Chemical Society. "'Lab On A Chip' Improves Success Of In Vitro Fertilization." ScienceDaily. ScienceDaily, 4 September 2008. <www.sciencedaily.com/releases/2008/09/080901215003.htm>.
American Chemical Society. (2008, September 4). 'Lab On A Chip' Improves Success Of In Vitro Fertilization. ScienceDaily. Retrieved August 28, 2014 from www.sciencedaily.com/releases/2008/09/080901215003.htm
American Chemical Society. "'Lab On A Chip' Improves Success Of In Vitro Fertilization." ScienceDaily. www.sciencedaily.com/releases/2008/09/080901215003.htm (accessed August 28, 2014).

Share This




More Health & Medicine News

Thursday, August 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mini Pacemaker Has No Wires

Mini Pacemaker Has No Wires

Ivanhoe (Aug. 27, 2014) Cardiac experts are testing a new experimental device designed to eliminate major surgery and still keep the heart on track. Video provided by Ivanhoe
Powered by NewsLook.com
After Cancer: Rebuilding Breasts With Fat

After Cancer: Rebuilding Breasts With Fat

Ivanhoe (Aug. 27, 2014) More than 269 million women are diagnosed with breast cancer each year. Many of them will need surgery and radiation, but there’s a new simple way to reconstruct tissue using a patient’s own fat. Video provided by Ivanhoe
Powered by NewsLook.com
Blood Clots in Kids

Blood Clots in Kids

Ivanhoe (Aug. 27, 2014) Every year, up to 200,000 Americans die from a blood clot that travels to their lungs. You’ve heard about clots in adults, but new research shows kids can get them too. Video provided by Ivanhoe
Powered by NewsLook.com
Radio Waves Knock out Knee Pain

Radio Waves Knock out Knee Pain

Ivanhoe (Aug. 27, 2014) Doctors have used radio frequency ablation or RFA to reduce neck and back pain for years. But now, that same technique is providing longer-term relief for patients with severe knee pain. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins