Featured Research

from universities, journals, and other organizations

3-week Radiation Therapy As Effective As 5 Weeks For Early-stage Breast Cancer, Study Suggests

Date:
September 22, 2008
Source:
American Society for Therapeutic Radiology and Oncology
Summary:
Early-stage breast cancer patients who receive a more intensive course of radiation to their whole breast over three weeks is as effective as the standard, less intensive five-week whole breast radiation and offers patients more convenience at a lower cost, thereby providing a better quality of life, according to a recent randomized, long-term study.

Early-stage breast cancer patients who receive a more intensive course of radiation to their whole breast over three weeks is as effective as the standard, less intensive five-week whole breast radiation and offers patients more convenience at a lower cost, thereby providing a better quality of life, according to a randomized, long-term study.

The cost of this shorter treatment, called accelerated hypofractionated whole breast irradiation, is two-thirds of the cost of the standard whole breast radiation. It is also less expensive then other new approaches such as partial breast irradiation.

"There has been renewed interest in hypofractioned whole breast irradiation, due to the potential radiation advantages, patient convenience, quality of life and lower costs. However, long-term effects were a potential concern," Timothy Whelan, M.D., lead author of the study and a radiation oncologist at the Juravinski Cancer Centre at McMaster University in Hamilton, Ontario, Canada, said. "We were surprised that the risk of local recurrence and side effects for women treated with accelerated whole breast irradiation was so low even at 12 years. Our study shows that this treatment should be offered to select women treated with early-stage breast cancer."

Many women with early-stage breast cancer are able to undergo breast conserving therapy to keep their breast after treatment. Typically, this means they first have surgery to remove the cancer (called a lumpectomy) followed by a course of radiation therapy to kill any cancer cells that may remain. The standard whole breast radiation therapy treatment takes approximately 15 minutes every day, Monday through Friday, for five weeks.

Between April 1993 and September 1996, researchers randomly assigned 1,234 women to be treated with either accelerated whole breast irradiation or standard whole breast irradiation. These women were followed for 12 years to determine if accelerated whole breast radiation was as effective as the standard treatment. At 10 years after treatment, cancer returned locally in 6.2 percent of patients treated with the accelerated radiation therapy, compared to 6.7 percent for those patients treated with standard therapy. Both groups of patients also had a good or excellent cosmetic outcome from the radiation treatments.

"This shorter treatment may not be for everyone, however, I would encourage women whose breast cancer is caught early to talk to their oncologist to see if they are a good candidate for this shorter therapy," Dr. Whelan added.

The abstract, "Long-Term Results of a Randomized Trial of Accelerated Hypofractionated Whole Breast Irradiation Following Breast Conserving Surgery in Women with Node-negative Breast Cancer," was presented September 22, 2008, in the plenary session at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston.


Story Source:

The above story is based on materials provided by American Society for Therapeutic Radiology and Oncology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Therapeutic Radiology and Oncology. "3-week Radiation Therapy As Effective As 5 Weeks For Early-stage Breast Cancer, Study Suggests." ScienceDaily. ScienceDaily, 22 September 2008. <www.sciencedaily.com/releases/2008/09/080922090753.htm>.
American Society for Therapeutic Radiology and Oncology. (2008, September 22). 3-week Radiation Therapy As Effective As 5 Weeks For Early-stage Breast Cancer, Study Suggests. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2008/09/080922090753.htm
American Society for Therapeutic Radiology and Oncology. "3-week Radiation Therapy As Effective As 5 Weeks For Early-stage Breast Cancer, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2008/09/080922090753.htm (accessed September 1, 2014).

Share This




More Health & Medicine News

Monday, September 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

Reuters - US Online Video (Aug. 30, 2014) California lawmakers pass a bill requiring universities to adopt "affirmative consent" language in their definitions of consensual sex, part of a nationwide drive to curb sexual assault on campuses. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
New Drug Could Reduce Cardiovascular Deaths

New Drug Could Reduce Cardiovascular Deaths

Newsy (Aug. 30, 2014) The new drug from Novartis could reduce cardiovascular deaths by 20 percent compared to other similar drugs. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins