Featured Research

from universities, journals, and other organizations

Key Proteins Identified In The Quest For Male Contraceptive

Date:
September 23, 2008
Source:
American Chemical Society
Summary:
In an advance toward a long-sought new male contraceptive, researchers in China have identified key proteins in men that suppress production of sperm and could become new targets for a future male birth control pill.

In an advance toward a long-sought new male contraceptive, researchers in China have identified key proteins in men that suppress production of sperm and could become new targets for a future male birth control pill.

Related Articles


Jiahao Sha and colleagues point out that scientists do not understand one effect of the male sex hormone, testosterone — how injections of the hormone suppress production of sperm. Building on a previous study showing almost total sperm suppression with an injectable testosterone combined with a synthetic hormone called levonorgestrel (LNG), the researchers sought new insights into how hormones affect sperm-producing cells in the testicles.

In a new study on men, they found that testosterone combined with LNG changed the body's production of 31 proteins compared to only 13 proteins for men given only testosterone. The scientists identified proteins that could serve as both targets for new male contraceptives as well as medications for treating infertility.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cui et al. Proteomic Analysis of Testis Biopsies in Men Treated with Injectable Testosterone Undecanoate Alone or in Combination with Oral Levonorgestrel as Potential Male Contraceptive. Journal of Proteome Research, 2008; 7 (9): 3984 DOI: 10.1021/pr800259t

Cite This Page:

American Chemical Society. "Key Proteins Identified In The Quest For Male Contraceptive." ScienceDaily. ScienceDaily, 23 September 2008. <www.sciencedaily.com/releases/2008/09/080922095433.htm>.
American Chemical Society. (2008, September 23). Key Proteins Identified In The Quest For Male Contraceptive. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2008/09/080922095433.htm
American Chemical Society. "Key Proteins Identified In The Quest For Male Contraceptive." ScienceDaily. www.sciencedaily.com/releases/2008/09/080922095433.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins