Featured Research

from universities, journals, and other organizations

Antioxidant Deficiency Linked To Pulmonary Hypertension

Date:
September 26, 2008
Source:
Wiley-Blackwell
Summary:
A recent study shows that a loss of antioxidants in the endothelial cells that line blood vessels in the lungs contributes to the loss of vasodilator effects and, ultimately, to the development of pulmonary hypertension. The findings appear in Clinical and Translational Science.

A recent study shows that a loss of antioxidants in the endothelial cells that line blood vessels in the lungs contributes to the loss of vasodilator effects and, ultimately, to the development of pulmonary hypertension.

The study, led by Serpil Erzurum of the Cleveland Clinic, evaluated antioxidant activities in patients with idiopathic pulmonary arterial hypertension (IPAH), a fatal disease characterized by progressive increase in pulmonary artery pressure and vascular resistance.

Erzurum's study found that the inactivation of these oxidants inside the cell is achieved mainly by the cell's own line of defense against oxidants. Additionally, the researchers determined that this process may contribute to low levels of nitric oxide, identified in IPAH and a fundamental component in the pathogenesis of pulmonary hypertension.

According to Dr. Erzurum, there is a potential long-term benefit to the care of patients with IPAH due to the study's findings. "Antioxidant augmentation in patients might be used to increase nitric oxide vasodilator effects, reduce pulmonary artery pressures and potentially improve clinical outcomes," she said.

The findings appear in Clinical and Translational Science.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "Antioxidant Deficiency Linked To Pulmonary Hypertension." ScienceDaily. ScienceDaily, 26 September 2008. <www.sciencedaily.com/releases/2008/09/080923164718.htm>.
Wiley-Blackwell. (2008, September 26). Antioxidant Deficiency Linked To Pulmonary Hypertension. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2008/09/080923164718.htm
Wiley-Blackwell. "Antioxidant Deficiency Linked To Pulmonary Hypertension." ScienceDaily. www.sciencedaily.com/releases/2008/09/080923164718.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins