Featured Research

from universities, journals, and other organizations

Blood Thinning Drug Linked To Increased Bleeding In Brain

Date:
October 1, 2008
Source:
American Academy of Neurology
Summary:
A new study shows that people who take the commonly used blood thinning drug warfarin may have larger amounts of bleeding in the brain and increased risk of death if they suffer a hemorrhagic stroke.

A new study shows that people who take the commonly used blood thinning drug warfarin may have larger amounts of bleeding in the brain and increased risk of death if they suffer a hemorrhagic stroke.

The study is published in the September 30, 2008, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Warfarin is commonly prescribed to prevent blood clotting. Studies have shown it helps prevent ischemic stroke for patients with an abnormal heart rhythm called atrial fibrillation. However, if the drug makes the blood too thin, it can increase the risk of brain hemorrhage, a type of stroke caused by bleeding in the brain.

The study involved 258 people who had brain hemorrhage, 51 of whom were taking warfarin. Participants were 69 years old on average and lived in or near Cincinnati. The group underwent brain scans to confirm the type of stroke. The brain scans were used to measure the size of the blood clots.

The study found that people who took warfarin and suffered a brain hemorrhage while their international normalized ratio (INR) was above three had about twice as much initial bleeding as those not taking warfarin. However, this effect was not seen in people whose blood was less likely to clot as determined by an INR of less than three. An INR test measures the blood's ability to clot.

"Warfarin is very effective for preventing ischemic strokes among people with atrial fibrillation and for most patients with this condition it is the right choice," said study author Matthew L. Flaherty, MD, with the University of Cincinnati and member of the American Academy of Neurology. "However, people who have bleeding into the brain while taking warfarin are at greater risk of dying than other people with hemorrhagic stroke. Our study may help to explain why. Fortunately, we did not see larger blood clots in people with an INR of less than three. For most patients on warfarin, the goal INR is between two and three. This shows the importance of good monitoring and adjustment of warfarin dose. People should talk to their doctors about the proper management of warfarin and learn the signs of stroke so they can get to an emergency room immediately if a stroke occurs."

To learn the five signs of stroke, visit http://www.giveme5forstroke.org. Give Me Five for Stroke is a joint campaign of the American Academy of Neurology, the American College of Emergency Physicians and the American Heart Association/American Stroke Association to encourage people to recognize stroke symptoms, call 9-1-1, and get to the emergency department.

The study was supported by the National Institute of Neurological Disorders and Stroke and a University of Cincinnati College of Medicine Medical Student Summer Research Fellowship.

 


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Blood Thinning Drug Linked To Increased Bleeding In Brain." ScienceDaily. ScienceDaily, 1 October 2008. <www.sciencedaily.com/releases/2008/09/080929163715.htm>.
American Academy of Neurology. (2008, October 1). Blood Thinning Drug Linked To Increased Bleeding In Brain. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2008/09/080929163715.htm
American Academy of Neurology. "Blood Thinning Drug Linked To Increased Bleeding In Brain." ScienceDaily. www.sciencedaily.com/releases/2008/09/080929163715.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) — In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) — A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) — President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins