Featured Research

from universities, journals, and other organizations

Artificial Pancreas Could Revolutionize Treatment Of Type 1 Diabetes

Date:
October 30, 2008
Source:
University of Virginia
Summary:
Researchers across the globe are testing a computerized, subcutaneous system that could one day transform the way Type 1 diabetics manage their disease.

Researchers at the University of Virginia and sites across the globe are testing a computerized, subcutaneous system that could one day transform the way Type 1 diabetics manage their disease.

U.Va. investigators have completed the first of several international artificial pancreas clinical trials to test an individually-"prescribed" control algorithm, which regulates blood glucose levels in Type 1 diabetics. U.Va.is one of seven centers worldwide funded by the Juvenile Diabetes Research Foundation to perform the novel closed-loop computer simulation of the human metabolic system.

Since late June, researchers have successfully tested the new system on five patients at the U.Va. Health System. Three additional patients participated in a parallel study at the University of Padova, Italy.

"Our initial results are very encouraging," said Boris Kovatchev, associate professor of psychiatry and neurobehavioral sciences and of systems and information engineering, who is leading U.Va.'s research team. "The system entirely maintained the patients' blood glucose levels, and the algorithm achieved excellent overnight control without any incidence of hypoglycemia."

Kovatchev, internationally known for his expertise in applying advanced computational methods to diabetes research, was one of the scientists who developed the system's novel algorithm, which allows for personalized treatment for each patient. By linking patients' glucose monitors with their insulin pumps, the "smart" program automatically regulates the amount of insulin a patient needs.

Researchers were granted Food and Drug Administration approval, based solely on computer simulation experiments, to test the artificial pancreas in humans, without any prior animal trials. The action cut research development time from several years to six months.

"This artificial pancreas could one day greatly improve the current methods of self-treatment for Type 1 diabetes," Kovatchev said. "Instead of a patient having to measure his or her blood sugar with a glucose meter several times a day and self-administer insulin injections, this system would continuously regulate the patient's blood glucose, much like the way a non-diabetic's pancreas functions."

Complete results from the initial clinical trials at the U.Va.Health System, the University of Padova and the University of Montpellier, France, are expected by the end of 2008.


Story Source:

The above story is based on materials provided by University of Virginia. Note: Materials may be edited for content and length.


Cite This Page:

University of Virginia. "Artificial Pancreas Could Revolutionize Treatment Of Type 1 Diabetes." ScienceDaily. ScienceDaily, 30 October 2008. <www.sciencedaily.com/releases/2008/10/081029104717.htm>.
University of Virginia. (2008, October 30). Artificial Pancreas Could Revolutionize Treatment Of Type 1 Diabetes. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2008/10/081029104717.htm
University of Virginia. "Artificial Pancreas Could Revolutionize Treatment Of Type 1 Diabetes." ScienceDaily. www.sciencedaily.com/releases/2008/10/081029104717.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins