Featured Research

from universities, journals, and other organizations

Pediatric Obesity May Alter Thyroid Function And Structure

Date:
December 4, 2008
Source:
The Endocrine Society
Summary:
In addition to its strong associations with hypertension, cardiovascular disease, and diabetes, pediatric obesity may induce alterations in thyroid function and structure, according to a new study.

In addition to its strong associations with hypertension, cardiovascular disease, and diabetes, pediatric obesity may induce alterations in thyroid function and structure, according to a new study.

Related Articles


Thyroid hormones drive metabolism, however demonstration of a direct or strong correlation of obesity with deficient thyroid function has been controversial, and previous studies provide conflicting conclusions. While some studies have found that thyroid disorders may lead to obesity, this recent study shows that in some cases, it is the obesity that may cause the disorder.

"Our study shows that alterations in thyroid function and structure are common in obese children and we may have uncovered the link," said Giorgio Radetti, M.D., of the Regional Hospital of Bolzano in Italy and lead author of the study. "We found an association between body mass index and thyroid hormone levels which suggests that fat excess may have a role in thyroid tissue modification."

This study evaluated 186 overweight and obese children over a period of nearly three years. Researchers measured subjects' thyroid hormone levels and thyroid antibodies and also performed a thyroid ultrasound.

The presence of thyroid antibodies would suggest a diagnosis of Hashimoto's thyroiditis, an autoimmune disease of the thyroid where T-cells attack the cells of the thyroid. In this study, 73 children did not show these antibodies, yet their ultrasound pattern was still suggestive of Hashimoto's thyroiditis.

"The ultrasound findings are a bit mysterious," said Dr. Radetti. "However, the findings do suggest the existence of a low-grade inflammation state, which has been known to characterize obesity."

Thyroid function has been shown to return to normal after weight loss, said Dr Radetti, raising the question of the potential reversibility of thyroid abnormalities shown on an ultrasound. However, researchers still do not know whether the persistence of thyroid abnormalities in obese children may also progress into chronic thyroid disease in early adulthood. Dr. Radetti says more studies are needed to answer these questions.

Other researchers working on the study include Wolfgang Kleon, Lucia Pappalardo, and Claudio Crivellaro of the Regional Hospital of Bolzano in Italy, Fabio Buzi of the University of Brescia in Italy, and Natascia di Iorgi and Mohamad Maghnie of the University of Genova in Italy.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Thyroid Function and Structure are Affected in Childhood Obesity,. Journal of Clinical Endocrinology & Metabolism, December 2008

Cite This Page:

The Endocrine Society. "Pediatric Obesity May Alter Thyroid Function And Structure." ScienceDaily. ScienceDaily, 4 December 2008. <www.sciencedaily.com/releases/2008/12/081203084312.htm>.
The Endocrine Society. (2008, December 4). Pediatric Obesity May Alter Thyroid Function And Structure. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2008/12/081203084312.htm
The Endocrine Society. "Pediatric Obesity May Alter Thyroid Function And Structure." ScienceDaily. www.sciencedaily.com/releases/2008/12/081203084312.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Liberia Releases Last Ebola Patient, But Threat Remains

Liberia Releases Last Ebola Patient, But Threat Remains

Newsy (Mar. 5, 2015) Liberia&apos;s last Ebola patient has been released, and the country hasn&apos;t recorded a new case in a week. However, fears of another outbreak still exist. Video provided by Newsy
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins