Featured Research

from universities, journals, and other organizations

Control Of Blood Vessels A Possible Weapon Against Obesity

Date:
January 8, 2009
Source:
Karolinska Institutet
Summary:
Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat more quickly, according to a new study. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes.

Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat more quickly, according to a new study from Karolinska Institutet. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes.

Related Articles


The growth of fat cells and their metabolism depend on oxygen and blood-borne nutrients. A possible way to regulate the amount of body fat – in order, for instance, to combat obesity – can therefore be to affect the development of blood vessels in the adipose tissue.

A team of researchers at Karolinska Institutet have now demonstrated the rapid development of blood vessels in the adipose tissue of mice exposed to low temperatures. This is followed in its turn by a transformation of the adipose tissue from ‘white’ fat to ‘brown’ fat, which has higher metabolic activity and which breaks down more quickly.

“This is the first time it’s been shown that blood vessel growth affects the metabolic activity of adipose tissue rather than vice versa,” says Professor Yihai Cao, who led the study. “If we can learn how to regulate the development of blood vessels in humans, we’d open up new therapeutic avenues for obesity and metabolic diseases like diabetes.”

Brown fat releases heat when it breaks down, and is mainly found in hibernating animals. In humans, it is found in newborn babies, but scientists believe by controlling blood vessel development that it might be possible to transform white fat to brown fat in adults as well.


Story Source:

The above story is based on materials provided by Karolinska Institutet. Note: Materials may be edited for content and length.


Journal Reference:

  1. Yuan Xue, Natasa Petrovic, Renhai Cao, Ola Larsson, Sharon Lim, Shaohua Chen, Helena M Feldmann, Zicai Liang, Zhengping Zhu, Jan Nedergaard, Barbara Cannon, Yihai Cao. Cold triggers VEGF-dependent but hypoxia-independent angiogenesis in adipose tissues and anti-VEGF agents modulate adipose tissue metabolism. Cell Metabolism, 6 January 2009

Cite This Page:

Karolinska Institutet. "Control Of Blood Vessels A Possible Weapon Against Obesity." ScienceDaily. ScienceDaily, 8 January 2009. <www.sciencedaily.com/releases/2009/01/090107085314.htm>.
Karolinska Institutet. (2009, January 8). Control Of Blood Vessels A Possible Weapon Against Obesity. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2009/01/090107085314.htm
Karolinska Institutet. "Control Of Blood Vessels A Possible Weapon Against Obesity." ScienceDaily. www.sciencedaily.com/releases/2009/01/090107085314.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins