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Microswimmers Make Big Splash For Improved Drug Delivery

Date:
January 13, 2009
Source:
American Chemical Society
Summary:
They may never pose a challenge to Olympic superstar Michael Phelps, but the "microswimmers" developed by researchers in Spain and the United Kingdom could break a long-standing barrier to improving delivery of medications for cancer and other diseases.

Tiny, magnetically controlled particles, called "microswimmers" could use by doctors to precisely deliver medicine to diseased tissue.
Credit: ACS

They may never pose a challenge to Olympic superstar Michael Phelps, but the "microswimmers" developed by researchers in Spain and the United Kingdom could break a long-standing barrier to improving delivery of medications for cancer and other diseases.

They describe the development of tiny, magnetically controlled particles, called "microswimmers," that doctors could use to precisely deliver medicine to diseased tissue.

In the new study, Pietro Tierno and colleagues note that scientists tried for years to develop tiny engines that can move micro and nanomachines through tight spaces, such as blood vessels and lab-on-a chip devices. But existing engines are slow, difficult to maneuver, and must undergo alterations in their shape, chemistry or temperature in order to work. The design of simple, more practical engines to power these tiny, robotic machines remains a major challenge, the researchers say.

The scientists describe a solution — tiny beads, about 1/25,000 of an inch in diameter, made of plastic and magnetic materials. When exposed to a magnetic field, the particles spun like a gyroscope and could be easily directed to move though narrow channels of liquids inside a glass plate, the researchers say. The scientists could control the speed of the "microswimmers" by varying the strength of the magnetic field.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Tierno et al. Magnetically Actuated Colloidal Microswimmers. The Journal of Physical Chemistry B, 2008; 112 (51): 16525 DOI: 10.1021/jp808354n

Cite This Page:

American Chemical Society. "Microswimmers Make Big Splash For Improved Drug Delivery." ScienceDaily. ScienceDaily, 13 January 2009. <www.sciencedaily.com/releases/2009/01/090112094740.htm>.
American Chemical Society. (2009, January 13). Microswimmers Make Big Splash For Improved Drug Delivery. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2009/01/090112094740.htm
American Chemical Society. "Microswimmers Make Big Splash For Improved Drug Delivery." ScienceDaily. www.sciencedaily.com/releases/2009/01/090112094740.htm (accessed April 17, 2014).

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