Featured Research

from universities, journals, and other organizations

Genetic Marker For Insecticide Resistance In Mosquitoes Identified

Date:
February 4, 2009
Source:
Liverpool School of Tropical Medicine
Summary:
The genetic basis for resistance to commonly-used insecticides in Anopheles funestus, one of the major malaria-carrying mosquitoes in Africa has been identified.

Research led by the Liverpool School of Tropical Medicine has identified the genetic basis for resistance to commonly-used insecticides in one of the major malaria-carrying mosquitoes in Africa. 

Related Articles


Malaria remains one of the biggest killers of children and pregnant women in the developing world.  Much of the effort to combat malaria is focused on controlling the mosquitoes which transmit the disease through the use of insecticides in bednets and indoor spraying. 

Mosquitoes can evolve to overcome the way in which insecticides work and the emergence of insecticide-resistant strains of mosquitoes is an increasing problem, therefore understanding more about its genetic and biological basis is critical.

The group, led by Dr Charles Wondji at LSTM, studied strains of the Anopheles funestus mosquito and identified a family of genes coding for enzymes known as cytochrome P450s, detecting two genes which were associated with resistance to pyrethroid insecticide.  Dr Hilary Ranson of the Liverpool School of Tropical Medicine, an author of the study, explained that these same genes were also recently identified with pyrethroid resistance in the other major malaria-carrying mosquito in Africa, Anopheles gambiae: 

"We expected to find that different species and populations would have different groups of genes responsible but they are very similar.  This is encouraging news because it means that work to overcome resistance in one species is likely to be effective against the other."

Furthermore, provided these genetic markers identified in laboratory populations of mosquitoes are equally predictive in the field – something currently being tested by Dr Wondji – this will overcome a major blocking point in the evaluation of wild mosquito populations.  Dr Ranson explained:  "Routine use of these molecular markers for resistance will provide early warning of future control problems due to insecticide resistance and should greatly enhance our ability to mitigate the potentially devastating effects of resistance on malaria control."


Story Source:

The above story is based on materials provided by Liverpool School of Tropical Medicine. Note: Materials may be edited for content and length.


Journal Reference:

  1. Wondji, C.S., Irving, H., Morgan, J., Lobo, N.F., Collins, F.H., Hunt, R.H., Coetzee, M., Hemingway, J., and Ranson, H. Two duplicated P450 genes are associated with pyrethroid resistance in Anopheles funestus, a major malaria vector. Genome Research, DOI: 10.1101/gr.087916.108

Cite This Page:

Liverpool School of Tropical Medicine. "Genetic Marker For Insecticide Resistance In Mosquitoes Identified." ScienceDaily. ScienceDaily, 4 February 2009. <www.sciencedaily.com/releases/2009/02/090204085518.htm>.
Liverpool School of Tropical Medicine. (2009, February 4). Genetic Marker For Insecticide Resistance In Mosquitoes Identified. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2009/02/090204085518.htm
Liverpool School of Tropical Medicine. "Genetic Marker For Insecticide Resistance In Mosquitoes Identified." ScienceDaily. www.sciencedaily.com/releases/2009/02/090204085518.htm (accessed October 26, 2014).

Share This



More Health & Medicine News

Sunday, October 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
Toxin-Packed Stem Cells Used To Kill Cancer

Toxin-Packed Stem Cells Used To Kill Cancer

Newsy (Oct. 25, 2014) — A Harvard University Research Team created genetically engineered stem cells that are able to kill cancer cells, while leaving other cells unharmed. Video provided by Newsy
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins