Featured Research

from universities, journals, and other organizations

Vitamin B12 identified As An Effective Canker Sore Therapy, Study Suggests

Date:
February 15, 2009
Source:
American Associates, Ben-Gurion University of the Negev
Summary:
Physicians have discovered that a nightly dose of vitamin B12 is a simple, effective and low risk therapy to prevent Recurrent Aphthous Stomatitis, better known as "canker sores." According to the lead researcher, "the frequency of RAS is as much as 25 percent in the general population."

A team of physicians at Ben-Gurion University of the Negev has discovered that a nightly dose of vitamin B12 is a simple, effective and low risk therapy to prevent Recurrent Aphthous Stomatitis (RAS), better known as "canker sores."

According to lead researcher Dr. Ilia Volkov, "the frequency of RAS is as much as 25 percent in the general population, however, until now, there has been no optimal therapeutic approach."

Dr.Volkov is a primary care physician in the Clalit Health Services and lecturer in Ben-Gurion University's Department of Family Medicine in its Faculty of Health Sciences.

The researchers tested the effect of vitamin B12 on 58 randomly selected RAS patients who received either a dose of 1,000 mcg of B12 by mouth at bedtime or a placebo, and were tested monthly for six months. Approximately three quarters (74 percent) of the patients of the treated group and only a third (32 percent) of the control group achieved remission at the end of the study.

According to the research, "The average outbreak duration and the average number of ulcers per month decreased in both groups during the first four months of the trial. However, the duration of outbreaks, the number of ulcers, and the level of pain were reduced significantly at five and six months of treatment with vitamin B12, regardless of initial vitamin B12 levels in the blood. During the last month of treatment a significant number of participants in the intervention group reached 'no aphthous ulcers status' (74.1% vs 32.0%; P < .01)."

The treated patients expressed greater comfort, reported less pain, fewer ulcers, and shorter outbreaks during the six months while among the control group the average pain level decreased during the first half of the period but increased during the second half.


Story Source:

The above story is based on materials provided by American Associates, Ben-Gurion University of the Negev. Note: Materials may be edited for content and length.


Journal Reference:

  1. Volkov et al. Effectiveness of Vitamin B12 in Treating Recurrent Aphthous Stomatitis: A Randomized, Double-Blind, Placebo-Controlled Trial. The Journal of the American Board of Family Medicine, 2009; 22 (1): 9 DOI: 10.3122/jabfm.2009.01.080113

Cite This Page:

American Associates, Ben-Gurion University of the Negev. "Vitamin B12 identified As An Effective Canker Sore Therapy, Study Suggests." ScienceDaily. ScienceDaily, 15 February 2009. <www.sciencedaily.com/releases/2009/02/090210092732.htm>.
American Associates, Ben-Gurion University of the Negev. (2009, February 15). Vitamin B12 identified As An Effective Canker Sore Therapy, Study Suggests. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2009/02/090210092732.htm
American Associates, Ben-Gurion University of the Negev. "Vitamin B12 identified As An Effective Canker Sore Therapy, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2009/02/090210092732.htm (accessed April 17, 2014).

Share This



More Health & Medicine News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com
Formerly Conjoined Twins Released From Dallas Hospital

Formerly Conjoined Twins Released From Dallas Hospital

Newsy (Apr. 16, 2014) Conjoined twins Emmett and Owen Ezell were separated by doctors in August. Now, nearly nine months later, they're being released from the hospital. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins