Featured Research

from universities, journals, and other organizations

Fibromyalgia Pain Linked To Central Nervous System Dysfunction

Date:
February 18, 2009
Source:
American Pain Society
Summary:
Widespread body pain in fibromyalgia patients is associated with specific brain metabolite abnormalities, according to new research.

Widespread body pain in fibromyalgia patients is associated with specific brain metabolite abnormalities, according to research in The Journal of Pain.

Related Articles


Scientists at Louisiana State University examined 16 fibromyalgia patients to assess the role in fibromyalgia pain played by metabolite abnormalities in the hippocampal region of the brain. The hippocampus is sensitive to the effects of stress exposure and can be affected in a variety of disorders, like fibromyalgia, which are associated with stressful experiences. Fibromyalgia is considered a stress-related disorder because of the frequent onset and exacerbation of pain symptoms. Brain imaging studies have shown there are central nervous system disturbances that occur in response to pain stimulation.

The researchers sought to explore the role of the hippocampus region in fibromyalgia pain, especially in pain perception, cognition and modulation of the central stress response.

From the analysis of subjects' brain scans, they found that exposure to chronic stress produces an increase hippocampal excitability that may play a role in the exaggerated sense of pain or hyperalgesia commonly experienced by fibromyalgia patients. Therefore, brain metabolite abnormalities in premenopausal fibromyalgia patients can disrupt the hippocampus region and inhibit brain activity required for modulating stress responses.


Story Source:

The above story is based on materials provided by American Pain Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. P. Wood, C. Ledbetter, M. Glabus, L. Broadwell, J. Patterson 2nd. Hippocampal Metabolite Abnormalities in Fibromyalgia: Correlation With Clinical Features. The Journal of Pain, 2008; DOI: 10.1016/j.jpain.2008.07.003

Cite This Page:

American Pain Society. "Fibromyalgia Pain Linked To Central Nervous System Dysfunction." ScienceDaily. ScienceDaily, 18 February 2009. <www.sciencedaily.com/releases/2009/02/090217123124.htm>.
American Pain Society. (2009, February 18). Fibromyalgia Pain Linked To Central Nervous System Dysfunction. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/2009/02/090217123124.htm
American Pain Society. "Fibromyalgia Pain Linked To Central Nervous System Dysfunction." ScienceDaily. www.sciencedaily.com/releases/2009/02/090217123124.htm (accessed February 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, February 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins