Featured Research

from universities, journals, and other organizations

Medical Researchers Test Bedside Monitoring Of Brain Blood Flow And Metabolism In Stroke Victims

Date:
March 10, 2009
Source:
University of Pennsylvania
Summary:
Scientists have completed the first successful demonstration of a noninvasive optical device to monitor cerebral blood flow in patients with acute stroke, a leading cause of disability and death.

A University of Pennsylvania team has completed the first successful demonstration of a noninvasive optical device to monitor cerebral blood flow in patients with acute stroke, a leading cause of disability and death.

The ultimate goal of this research is to improve the management of patients with stroke and other brain disorders by providing continuous bedside monitoring of brain blood flow and metabolism.

“Our preliminary study demonstrates that blood flow changes can be reliably detected from stroke patients and also suggests that blood flow responses vary significantly from patient to patient,” lead author Turgut Durduran said.

Ischemic stroke is the leading cause of morbidity and long-term disability in the United States, with projected cost of stroke care estimated at trillions of dollars during the next five decades. Stroke accounts for nearly 10 percent of deaths in the western hemisphere and about 5 percent of health-care costs.

The device being developed uses embedded optical probes that are placed over major cortical blood vessels in each hemisphere of the brain. The technology, diffuse correlation spectroscopy is a non-invasive system that uses lasers, photon-counting detectors, radio-frequency electronics, data processors and a computer monitor to display user-friendly images of functional information to physicians and nurses.

“What we have demonstrated is a working prototype of a non-invasive brain probe that uses diffusing light to detect physiological changes such as blood flow, blood-oxygen saturation and hemoglobin concentration to inform clinicians about their treatments,” Arjun Yodh, professor of physics in the School of Arts and Sciences at Penn and principal investigator of the study, said.

The study is part of a $2.8 million, five-year Bioengineering Research Partnership grant from the National Institutes of Health and the University of Pennsylvania Comprehensive Neuroscience Center. BRP grants are awarded to interdisciplinary teams that combine basic, applied and translational research for important biological or medical problems. Yodh is joined by Rick Van Berg from the High Energy group of the Department of Physics in the School of Arts and Sciences and clinical collaborators John Detre, Joel Greenberg and Scott Kasner from the Department of Neurology in the School of Medicine at Penn.

“Stroke is caused by a reduction in blood flow to the brain, yet brain blood flow is rarely if ever measured in stroke patients because most existing methods to measure blood flow require costly instrumentation that is not portable,” Detre said. “The ability to quantify tissue hemodynamics at the bedside would provide new opportunities both to learn more about blood-flow changes in patients with acute stroke and to optimize interventions to increase blood flow for individual patients, potentially even allowing these interventions to be administered before the onset of new neurological symptoms.”


Story Source:

The above story is based on materials provided by University of Pennsylvania. Note: Materials may be edited for content and length.


Cite This Page:

University of Pennsylvania. "Medical Researchers Test Bedside Monitoring Of Brain Blood Flow And Metabolism In Stroke Victims." ScienceDaily. ScienceDaily, 10 March 2009. <www.sciencedaily.com/releases/2009/03/090302133308.htm>.
University of Pennsylvania. (2009, March 10). Medical Researchers Test Bedside Monitoring Of Brain Blood Flow And Metabolism In Stroke Victims. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2009/03/090302133308.htm
University of Pennsylvania. "Medical Researchers Test Bedside Monitoring Of Brain Blood Flow And Metabolism In Stroke Victims." ScienceDaily. www.sciencedaily.com/releases/2009/03/090302133308.htm (accessed August 2, 2014).

Share This




More Health & Medicine News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins