Featured Research

from universities, journals, and other organizations

How Stem Cells Develop Into Blood Cells

Date:
March 12, 2009
Source:
McMaster University
Summary:
How messages sent within stem cells through a specific communication pathway can trigger the cells to specialize and become blood cells in humans has been discovered by scientists of the McMaster Stem Cell and Cancer Research Institute.

How messages sent within stem cells through a specific communication pathway can trigger the cells to specialize and become blood cells in humans, has been discovered by scientists of the McMaster Stem Cell and Cancer Research Institute.

The finding, to be published in the March 6 issue of Cell Stem Cell, marks the first time scientists have demonstrated the importance of the pathway, known as the noncanonical Wnt, in inducing blood formation in humans or any other species. The pathway works by organizing the cells so that they can respond to signals for blood development.

Mick Bhatia, director of the McMaster Stem Cell and Cancer Research Institute, is the lead investigator of the study, which involved researchers from McMaster University, Howard Hughes Medical Institute and the Randall T. Moon Institute for Stem Cell and Regenerative Medicine at the University of Washington.

"By directing cell differentiation, this method provides the most efficient way to produce blood cells that we are aware of to date," said Bhatia, a professor in the Department of Biochemistry and Biomedical Sciences at McMaster.

"The work also provides a new way to make blood from human stem cells that could be used for clinical applications to regenerate the immune and blood system in patients, including those with leukemia or undergoing cancer therapies that indirectly destroy the immune and blood system."

Stem cells are the building blocks of every organ and tissue in the body. Through the process of cellular differentiation, moving from a less specialized cell to a more specialize cell, stem cells have the ability to become any type of cell in the body including bone, muscle and blood cells.

In addition to the primary finding, the researchers also looked at second pathway and found that, unlike the first, it did not trigger the formation of blood cells. However, the second pathway did play a role in temporarily increasing the production of blood cells.

This project was funded by the Canadian Cancer Society with additional support from the Canadian Institutes for Health Research and the Stem Cell Network.


Story Source:

The above story is based on materials provided by McMaster University. Note: Materials may be edited for content and length.


Cite This Page:

McMaster University. "How Stem Cells Develop Into Blood Cells." ScienceDaily. ScienceDaily, 12 March 2009. <www.sciencedaily.com/releases/2009/03/090305121651.htm>.
McMaster University. (2009, March 12). How Stem Cells Develop Into Blood Cells. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2009/03/090305121651.htm
McMaster University. "How Stem Cells Develop Into Blood Cells." ScienceDaily. www.sciencedaily.com/releases/2009/03/090305121651.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins