Featured Research

from universities, journals, and other organizations

Risk Of Aggressive Breast Cancer Subtype Three Times Higher For African-American Women

Date:
April 3, 2009
Source:
Breast Cancer Research
Summary:
Lifestyle, age and weight have all been considered as risk factors for breast cancer. A new study has found that even taking these factors into consideration, African-American women face three times the risk of developing an aggressive "triple negative tumor" compared to women of other racial backgrounds.

Lifestyle, age and weight have all been considered as risk factors for breast cancer. A new study has found that even taking these factors into consideration, African-American women face three times the risk of developing an aggressive 'triple negative tumour' compared to women of other racial backgrounds.

In the US, which has the highest rate of breast cancer in the world, the overall incidence of breast cancer is lower in black women than in white women. Yet when black women do get breast cancer, it tends to be more advanced when diagnosed, has a higher risk or recurring and a less favourable outcome.

A research team led by Dr Carol Rosenberg at Boston University School of Medicine searched hospital records from the Boston Medical Center, focusing on 415 breast cancer cases. The team looked at clinical features particularly patient age, weight and race/ethnicity, and pathological features including the triple-negative pattern - tumours that lack expression of the estrogen receptor, the progesterone receptor and the HER2 gene

According to Rosenberg, "The odds of having a triple negative tumour were three times higher for black women than for non-black women in the study. Previously, it was known that pre-menopausal black women had more triple negative tumors. What we found that was new was that these tumours were just as common in black women diagnosed before or after age 50, and in those who were or were not obese."

Rosenberg adds, "The higher prevalence of triple negative breast tumours in black women in all age and weight categories likely contributes to black women's unfavourable breast cancer prognosis."


Story Source:

The above story is based on materials provided by Breast Cancer Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. Lesley Stead, Timothy L Lash, Jerome Sobieraj, Dorcas Chi, Jennifer Westrup, Marjory Charlot, Rita Blanchard, John-cho Lee, Thomas King and Carol L Rosenberg. Triple negative breast cancers are increased in black women regardless of age or body mass index. Breast Cancer Research, (in press)

Cite This Page:

Breast Cancer Research. "Risk Of Aggressive Breast Cancer Subtype Three Times Higher For African-American Women." ScienceDaily. ScienceDaily, 3 April 2009. <www.sciencedaily.com/releases/2009/03/090324200932.htm>.
Breast Cancer Research. (2009, April 3). Risk Of Aggressive Breast Cancer Subtype Three Times Higher For African-American Women. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/03/090324200932.htm
Breast Cancer Research. "Risk Of Aggressive Breast Cancer Subtype Three Times Higher For African-American Women." ScienceDaily. www.sciencedaily.com/releases/2009/03/090324200932.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins