Featured Research

from universities, journals, and other organizations

News From Space For Osteoporosis Patients On Earth: Resistance Is Not Futile

Date:
April 1, 2009
Source:
Federation of American Societies for Experimental Biology
Summary:
Results of a space experiment have yielded a giant leap for science that could translate into an important step for mankind in the ongoing battle against osteoporosis. In the report, a team of Italian scientists show for the first time that a lack of resistance (i.e., gravity) activates bone-destroying cells.

Results of a space experiment published online in The FASEB Journal have yielded a giant leap for science that could translate into an important step for mankind in the ongoing battle against osteoporosis. In the report, a team of Italian scientists show for the first time that a lack of resistance (i.e., gravity) activates bone-destroying cells. This outcome helps explain more completely why bedridden patients and astronauts experience bone loss and provides an entirely new drug target for stopping the process.

Related Articles


"This study cuts straight to the bone in terms of why our skeletons deteriorate with disuse," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "As is the case with human intelligence, bone loss is an example of 'use it or lose it.' This study from space has pinpointed the cellular culprits that destroy our bones when we don't use them to support weight."

Using two sets of bone-destroying cells, called "osteoclasts," obtained from the bone marrow of mice femurs, the scientists launched one set into space via the European Space Agency's 2007 FOTON-M3 mission and kept the other set on Earth. On the satellite, the cells were maintained in custom-designed bioreactors equipped with automatic nutrient providers. At the same time, the other set of cells were kept in the same type of bioreactors on the Earth's surface. After twelve days, the experiment was stopped and the cells were examined. The analysis revealed an increase in genes involved in osteoclast maturation and activity, as well as increased bone loss when compared to the cells on Earth.

"Space might be the final frontier, but we've got some serious hurdles to clear before we conquer microgravity, and bone loss is one of them," Weissmann added. "Even here on Earth, we all face bone loss. Osteoporosis inexorably hits men and women alike, and this European study points to one cause: lack of resistance."

According to NASA, an astronaut could lose as much as 10 to 15 percent of pre-flight bone mass after only six months in space. The National Osteoporosis Foundation reports that at least 25 million people in the United States suffer from bone loss.


Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology. Note: Materials may be edited for content and length.


Cite This Page:

Federation of American Societies for Experimental Biology. "News From Space For Osteoporosis Patients On Earth: Resistance Is Not Futile." ScienceDaily. ScienceDaily, 1 April 2009. <www.sciencedaily.com/releases/2009/03/090330091702.htm>.
Federation of American Societies for Experimental Biology. (2009, April 1). News From Space For Osteoporosis Patients On Earth: Resistance Is Not Futile. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2009/03/090330091702.htm
Federation of American Societies for Experimental Biology. "News From Space For Osteoporosis Patients On Earth: Resistance Is Not Futile." ScienceDaily. www.sciencedaily.com/releases/2009/03/090330091702.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
WHO Says Male Ebola Survivors Should Abstain From Sex

WHO Says Male Ebola Survivors Should Abstain From Sex

Newsy (Nov. 28, 2014) — WHO cites four studies that say Ebola can still be detected in semen up to 82 days after the onset of symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins